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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
76 Results for "
Epimer.
" in MedChemExpress (MCE) Product Catalog:
Products (76)
76 Results for "Epimer." in MCE Product Catalog:
Target:
Cat. No.: HY-176823
CAS No.: 2381196-78-5
PROTAC SGK3 degrader-2 is the cis epimer of PROTAC SGK3 degrader-1 (SGK3-PROTAC1) (HY-125878). PROTAC SGK3 degrader-2 exhibits inhibitory activity against SGK3, SGK1 and S6K1, with IC50 values of 0.6 μM, 1.4 μM and 1.7 μM, respectively, but fails to degrade SGK3. PROTAC SGK3 degrader-2 can serve as a control compound to investigate the specific effects of SGK3 degradation mediated by SGK3-PROTAC1 .
Cat. No.: HY-137516A
CAS No.: 2502156-12-7
LC-2 epimer is a differential isomer of LC-2. LC-2 is a mutation-selective PROTAC depressant for KRAS and contains a ligand for the von Hippel Lindau E3 ligase linked to the KRAS inhibitor MRTX849 .
Cat. No.: HY-N0504S1
CAS No.: 2508138-69-8
Synonyms: Mevinolin-d9 (epimer mixture)
Cat. No.: HY-126069
CAS No.: 85026-51-3
Synonyms: 15(R)-Ciloprost; 15(R)-ZK 36374
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15(R)-Iloprost is the unnatural or inverted C-15 epimer of lloprost (HY-A0096) .
Cat. No.: HY-N0210S6
CAS No.: 64429-86-3
Synonyms: D-(+)-Galactose-d1-1
Cat. No.: HY-N0210S7
CAS No.: 478518-70-6
Synonyms: D-(+)-Galactose-d1-2
Cat. No.: HY-N0210S12
CAS No.: 370565-96-1
Synonyms: D-(+)-Galactose-13C,d1
Cat. No.: HY-N0210S2
CAS No.: 478518-58-0
Synonyms: D-(+)-Galactose-13C-3
Cat. No.: HY-N0210S3
CAS No.: 478518-60-4
Synonyms: D-(+)-Galactose-13C-4
Cat. No.: HY-N0210S4
CAS No.: 478518-62-6
Synonyms: D-(+)-Galactose-13C-5
Cat. No.: HY-201296A
CAS No.: 17515-36-5
Synonyms: TUCA sodium
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Tauroursocholic acid (TUCA) sodium is a taurine-conjugated form of the bile acid ursocholic acid and the 7β-hydroxy epimer of Taurocholic acid (HY-B1788). Tauroursocholic acid sodium exists in abundance during the biliary tract cancer, disrupting the balance and cellular toxicity of bile acids and inducing carcinogenesis through oxidative DNA damage and DNA mutation. Tauroursocholic acid (TUCA) sodium can be used for biliary tract cancer research .
Cat. No.: HY-32351B
CAS No.: 73809-05-9
Synonyms: 3-epi-25-Hydroxy cholecalciferol
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3-epi-25-hydroxy Vitamin D3 is the C-3 epimer of 25-hydroxy vitamin D3.1 Dietary administration of 3-epi-25-hydroxy vitamin D3 (0.5 and 1 IU/g) decreases levels of serum parathyroid hormone (PTH) in male, but not female, weanling rats.
Cat. No.: HY-139620A
MS83 epimer 1 is the epimer of MS83 (HY-139620). MS83 is a proof-of-concept PROTAC by linking the KEAP1 ligand to a BRD4/3/2 binder .
Cat. No.: HY-106365A
CAS No.: 144459-71-2
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Rofleponide epimer is a compound with anti-inflammatory activity. Rofleponide epimer has shown high selectivity in the lungs in experiments. Rofleponide epimer exhibits excellent pharmacological properties by efficiently binding to the rat thymic glucocorticoid receptor. The biotransformation rate of Rofleponide epimer is 10 times higher than that of other known similar drugs, indicating that it has potential application value in inhibiting inflammatory diseases involving mucosa .
Cat. No.: HY-145263A
Purity: ≥95.0%
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VD2173 epimer-1 is a racemic mixture of VD2173 (HY-145263) .
Cat. No.: HY-101390D
CAS No.: 120054-86-6
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(R)-Niguldipine, a R-epimer of Niguldipine (HY-101390B), is a calcium channel antagonist. (R)-Niguldipine exerts a vasodilatory effect by blocking calcium channels and reducing the transmembrane influx of calcium ions. (R)-Niguldipine can inhibit U-46619 (HY-108566)-induced coronary artery contraction in guinea pig Langendorff hearts (pID50 of 9.93), has high affinity for calcium channel binding sites on guinea pig skeletal muscle membranes (Ki of 8.10), and lowers blood pressure in spontaneously hypertensive rats (pED30 of 5.55). (R)-Niguldipine can improve cardiovascular diseases such as hypertension, angina pectoris, and arrhythmias .
Cat. No.: HY-160109A
CAS No.: 1334320-77-2
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Ac5GalNTGc epimer is an analogue of hexosamine and the racemate of Ac5GalNTGc (HY-160109). Ac5GalNTGc is a potent, peracetylated C-2 thioglycolyl-substituted GalNAc analog that efficiently inhibits mucin-type O-glycan biosynthesis. Ac5GalNTGc reduces leukocyte sialyl-Lewis-X expression and inhibits L-/P-selectin mediated rolling under flow, as well as P-selectin dependent leukocyte-platelet adhesion. Ac5GalNTGc exhibits anti-inflammatory activity in a thioglycollate-induced acute peritonitis model. Ac5GalNTGc can be used for studies of O-glycan/mucin biology, inflammation, and related translational research .
Cat. No.: HY-100885B
CAS No.: 1562406-26-1
Synonyms: (R)-NUC-1031; (R)-Fosgemcitabine palabenamide
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(R)-Acelarin ((R)-NUC-1031) is the R-epimer of Acelarin (HY-100885) .
Cat. No.: HY-157660
CAS No.: 21562-54-9
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15(R)-Prostaglandin F1α (compound 10) is the C-15 epimer of PGF1α .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
