32 Results for "

PTPN2

" in MedChemExpress (MCE) Product Catalog:
Products (32)

32 Results for "PTPN2" in MCE Product Catalog:

  • Targets Recommended:
  • Recombinant Proteins Recommended:
Cat. No.: HY-156608
CAS No.: 2948340-59-6
Target:  

Phosphatase

Research Areas:  

Cancer

Anticancer agent 144 (compound 444) is a dual PTPN2/PTP1B inhibitor with IC50 values <2.5 nM. Anticancer agent 144 can be used in cancer research .
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Cat. No.: HY-181255
CAS No.: 3112461-52-3
Target:  

Phosphatase

Research Areas:  

Cancer

PTPN2-IN-3 (example 52) is a PTPN2 inhibitor that can be used in tumor research .
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Cat. No.: HY-156607
CAS No.: 2948339-38-4
Target:  

Phosphatase

Research Areas:  

Cancer

Anticancer agent 143 (compound 369) is a dual PTPN2/PTP1B inhibitor with IC50 values <2.5 nM. Anticancer agent 143 can be used in cancer research .
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Cat. No.: HY-184258
CAS No.: 2504233-60-5
Target:  

Ligands for E3 Ligase

Research Areas:  

Others

CRBN ligand-905 is a naphtholactam-based CRBN E3 ligase ligand used in the design of PTPN2 PROTAC degraders PD-305 (HY-183937) .
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Cat. No.: HY-183937A
Target:  

PROTACs Phosphatase STAT

Research Areas:  

Cancer

PD-305 is a selective PTPN2 PROTAC degrader, with DC50 values of 0.25 nM and 5.11 nM against PTPN2 and PTPN1, respectively. PD-305 enhances IFN-γ-induced STAT1 phosphorylation, inhibits the proliferation of IFN-γ-stimulated colorectal cancer cells, promotes CD8 + T cell activation, enhances the tumor-killing activity of T cells, and suppresses tumor growth in mouse models. PD-305 can be used for the research of colorectal cancer .
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Cat. No.: HY-P76103A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PTPN2; TC48; Prev. PTPT; Tyrosine-Protein Phosphatase Non-Receptor Type; TCPTP; T-Cell Protein Tyrosine Phosphatase; TCELLPTP; T-Cell Protein-Tyrosine Phosphatase; TC-PTP; Protein-Tyrosine-Phosphatase; TC45; PTN2; Protein Tyrosine Phosphatase Non-Receptor
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P76103
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PTPN2; TC48; Prev. PTPT; Tyrosine-Protein Phosphatase Non-Receptor Type; TCPTP; T-Cell Protein Tyrosine Phosphatase; TCELLPTP; T-Cell Protein-Tyrosine Phosphatase; TC-PTP; Protein-Tyrosine-Phosphatase; TC45; PTN2; Protein Tyrosine Phosphatase Non-Receptor
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P76104
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: PTPN2; TC48; Prev. PTPT; Tyrosine-Protein Phosphatase Non-Receptor Type; TCPTP; T-Cell Protein Tyrosine Phosphatase; TCELLPTP; T-Cell Protein-Tyrosine Phosphatase; TC-PTP; Protein-Tyrosine-Phosphatase; TC45; PTN2; Protein Tyrosine Phosphatase Non-Receptor
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-W733139
CAS No.: 2655646-64-1
Target:  

Ligands for E3 Ligase

Research Areas:  

Others

3-[2-Oxo-6-(4-Pip)-Bz[cd]indol-1-yl]-Pip-2,6-dione is a CRBN ligand, which can be used for the synthesis of PROTACs, such as PROTAC PTPN2 degrader-2 (HY-153938) .
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Cat. No.: HY-P76669
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PTPN2; TC48; Prev. PTPT; Tyrosine-Protein Phosphatase Non-Receptor Type; TCPTP; T-Cell Protein Tyrosine Phosphatase; TCELLPTP; T-Cell Protein-Tyrosine Phosphatase; TC-PTP; Protein-Tyrosine-Phosphatase; TC45; PTN2; Protein Tyrosine Phosphatase Non-Receptor
Species:  
Mouse
Source:  
Sf9 insect cells
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Cat. No.: HY-156606
CAS No.: 2948338-60-9
Target:  

Phosphatase

Research Areas:  

Cancer

Anticancer agent 142 (compound 235) is a PTPN inhibitor, with the potential to study cancer .
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Cat. No.: HY-P87102
Synonyms: Protein tyrosine phosphatase non receptor type 2 antibody; PTN2 antibody; PTN2_HUMAN antibody; PTPN 2 antibody; PTPN2 antibody; PTPT antibody; T cell protein tyrosine phosphatase antibody; T-cell protein-tyrosine phosphatase antibody; TC PTP antibody; TCELLPTP antibody; Protein tyrosine phosphatase non receptor type 2 antibody; PTN2 antibody; PTN2_HUMAN antibody; PTPN 2 antibody; PTPN2 antibody; PTPT antibody; T cell protein tyrosine phosphatase antibody; T-cell protein-tyrosine phosphatase antibody; TC PTP antibody; TCELLPTP antibody; TCPTP antibody; Tyrosine protein phosphatase non receptor type 2 antibody; Tyrosine-protein phosphatase non-receptor type 2 antibody;

Host:  

Rabbit

Application:  

WB, FC

Reactivity:  

Human, Mouse, Rat

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