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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
34 Results for "
compulsive
" in MedChemExpress (MCE) Product Catalog:
Products (34)
34 Results for "compulsive" in MCE Product Catalog:
Cat. No.: HY-W1123900
CAS No.: 2945111-66-8
Target:
Research Areas:
5-HT2A agonist 3 (Compound P-141) is a selective 5-hydroxytryptamine 2A receptor (5-HT2A) agonist with an EC50 value of 13.80 nM. 5-HT2A agonist 3 is promising for research of mental illnesses such as depression, post-traumatic stress disorder, obsessive-compulsive disorder, and central nervous system disorders .
Cat. No.: HY-B0773
CAS No.: 217797-14-3
Synonyms: BRL29060 mesylate
Target:
Cytochrome P450 5-HT Receptor NO Synthase Apoptosis Serotonin Transporter Estrogen Receptor/ERR
Research Areas:
Paroxetine (BRL29060) mesylate is an orally active and selective serotonin reuptake inhibitor (SSRI) and apoptosis inducer with blood-brain barrier permeability. Paroxetine mesylate inhibits nitric oxide synthase and CYP2D6, induces desensitization of 5-HT1A/1B/1D autoreceptors, downregulates 5-HT2 receptors, and promotes the production of inflammatory cytokines. Paroxetine mesylate is a weak norepinephrine (NE) uptake inhibitor and possesses antitumor activity. Paroxetine mesylate is widely used in research concerning depression, obsessive-compulsive disorder, panic disorder, social phobia, generalized anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, hot flashes, and related conditions .
Cat. No.: HY-B0457AR
CAS No.: 303-49-1
Synonyms: Chlorimipramine (Standard); G-34586 (Standard); NSC-169865 (Standard)
Research Areas:
Clomipramine (Standard) is the analytical standard of Clomipramine. This product is intended for research and analytical applications. Clomipramine (Chlorimipramine) is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD) .
Cat. No.: HY-15401A
CAS No.: 428868-35-3
Cat. No.: HY-B0457S2
Synonyms: Chlorimipramine-13C,d3 hydrochloride; G-3458613C,d3 hydrochloride; NSC-169865-13C,d3 hydrochloride
Cat. No.: HY-101300R
CAS No.: 40600-13-3
Synonyms: LD 3098 hydrochloride (Standard)
Research Areas:
Cirazoline (hydrochloride) (Standard) is the analytical standard of Cirazoline (hydrochloride). This product is intended for research and analytical applications. Cirazoline hydrochloride (LD 3098 hydrochloride) is a potent competitive full?α1A-adrenergic receptor (α1A-AR) agonist (Ki=120 nM) and only a partial agonist at α1B-AR (Ki= 960 nM) and α1D-AR (Ki=660 nM) .
Cat. No.: HY-111124
CAS No.: 923932-43-8
Synonyms: BRL29060-d2
Cat. No.: HY-122272S
CAS No.: 923932-45-0
Synonyms: BRL29060-d4
Cat. No.: HY-122272S2
CAS No.: 1435728-63-4
Synonyms: BRL29060-d6-1
Cat. No.: HY-P703209
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: SLC6A4; Serotonin Transporter 1; Prev. HTT; 5HTT; Prev. OCD1; SERT; 5-HTT; Na+/Cl- Dependent Serotonin Transporter; SERT1; Obsessive-compulsive Disorder 1; Solute Carrier Family 6 (Neurotransmitter Transporter, Serotonin), Member 4; Transporter; Solute Ca
Species:
Human
Source:
HEK293
Cat. No.: HY-P703210
Synonyms: SLC6A4; Serotonin Transporter 1; Prev. HTT; 5HTT; Prev. OCD1; SERT; 5-HTT; Na+/Cl- Dependent Serotonin Transporter; SERT1; Obsessive-compulsive Disorder 1; Solute Carrier Family 6 (Neurotransmitter Transporter, Serotonin), Member 4; Transporter; Solute Ca
Species:
Human
Source:
HEK293
Cat. No.: HY-122272A
CAS No.: 72471-80-8
Synonyms: BRL29060 acetate
Target:
Cytochrome P450 5-HT Receptor NO Synthase Apoptosis Serotonin Transporter Estrogen Receptor/ERR
Research Areas:
Paroxetine (BRL29060) acetate is an orally active and selective serotonin reuptake inhibitor (SSRI) and apoptosis inducer with blood-brain barrier permeability. Paroxetine acetate inhibits nitric oxide synthase and CYP2D6, induces desensitization of 5-HT1A/1B/1D autoreceptors, downregulates 5-HT2 receptors, and promotes the production of inflammatory cytokines. Paroxetine acetate is a weak norepinephrine (NE) uptake inhibitor and possesses antitumor activity. Paroxetine acetate is widely used in research concerning depression, obsessive-compulsive disorder, panic disorder, social phobia, generalized anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, hot flashes, and related conditions .
Cat. No.: HY-103127
CAS No.: 1539266-32-4
Target:
Research Areas:
25CN-NBOH hydrochloride exhibits agonist activity at the 5-HT2a receptor, shows 90- to 100-fold selectivity over the 5-HT2c receptor, and possesses blood-brain barrier permeability . 25CN-NBOH hydrochloride acts as an interoceptive agent with partial agonist-like properties . 25CN-NBOH hydrochloride serves as a pharmacological tool for 5-HT2A receptor research, and its tritiated form functions as a selective agonist radioligand . 25CN-NBOH hydrochloride can be used to investigate diseases characterized by cognitive rigidity, schizophrenia, obsessive-compulsive disorder, depression, pain, inflammation, migraine, and cluster headache .
Cat. No.: HY-182453
CAS No.: 2849392-47-6
Target:
Research Areas:
RM1490 (Compound 251) acts as an inhibitor of μ-opioid receptor (MOR) (IC50 ≤ 300 nM), an activator of δ-opioid receptor (DOR) (EC50 > 3000 nM), and an inhibitor of κ-opioid receptor (KOR) (IC50 ≤ 300 nM). RM1490 is applicable to the research of neuropsychiatric disorders .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
