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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
40 Results for "
ssDNA
" in MedChemExpress (MCE) Product Catalog:
Products (40)
40 Results for "ssDNA" in MCE Product Catalog:
Cat. No.: HY-150623
CAS No.: 522660-61-3
SARS-CoV-2 nsp13-IN-2 (Compound C2) is a SARS-CoV-2 non-structural protein 13 (nsp13) small-molecule inhibitor with an IC50 of 42 μM against nsp13 ssDNA + ATPase .
Cat. No.: HY-P10680
Cat. No.: HY-D0922
CAS No.: 1284240-77-2
Target:
Research Areas:
Cy3.5 is a cyanine-based red fluorescent dye (Ex/Em ≈ 560-581/600-612 nm). After covalent conjugation with proteins, Cy3.5 exhibits extraordinary fluorescence enhancement with minimal quenching even at high labeling ratios. Cy3.5 can form a FRET dye pair with Cy5.5, which maintains stable FRET efficiency in various biochemical buffers and deoxygenated systems. Cy3.5 is applicable to studies related to fluorescent labeling of antibodies/proteins, single-molecule FRET imaging of double-stranded DNA and nucleosomes, SPION functionalization, in vivo tracing, and other relevant research .
Cat. No.: HY-150626
CAS No.: 912799-11-2
SARS-CoV-2 nsp13-IN-5 (compound C6) is a potent SARS-CoV-2 nsp13 inhibitor with IC50 values of 50 and 55 μM for ssDNA + ATPase and ssDNA - ATPase. SARS-CoV-2 nsp13-IN-5 can be used for researching anti-COVID-19 .
Cat. No.: HY-150632
CAS No.: 951588-85-5
SARS-CoV-2 nsp13-IN-6 (compound C5) is a potent SARS-CoV-2 non-structural protein 13 (nsp13) inhibitor with IC50 values of 27 and 33 μM for ssDNA + ATPase and ssDNA - ATPase. SARS-CoV-2 nsp13-IN-6 can be used for researching anti-COVID-19 .
Cat. No.: HY-110286R
CAS No.: 21373-30-8
Target:
Research Areas:
6-Hydroxy-DOPA (Standard) is the analytical standard of 6-Hydroxy-DOPA. This product is intended for research and analytical applications. 6-Hydroxy-DOPA is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer .
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DNA, 5'-GGGCGGGGCGGACGAGACAGTAAGGGCTGTGGGTGTGGTG-3', sodium salt
Cat. No.: HY-160046
Cat. No.: HY-150624
CAS No.: 1015582-31-6
SARS-CoV-2 nsp13-IN-3 (Compound C3) is a SARS-CoV-2 non-structural protein 13 (nsp13) small-molecule inhibitor with an IC50 of 32 μM against nsp13 ssDNA + ATPase .
Cat. No.: HY-160049
Research Areas:
BC15 aptamer sodium is an ssDNA aptamer targeting the intracellular protein hnRNP A1, which is highly expressed in cancerous liver tissue. BC15 aptamer sodium specifically recognizes breast cancer cells and can be used to detect cancer cells in other pathological types of breast cancer tissue .
Cat. No.: HY-169622
CAS No.: 103056-35-5
RAD51-IN-9 (Compound 3a) is a RAD51 inhibitor that can inhibit the binding of RAD51 to ssDNA with an IC50 of 17.85 μM. RAD51-IN-9 has a LD50 against HEK293 cells of 40.21 μM. RAD51-IN-9 can sensitize cells to Mitomycin C (HY-13316) .
Cat. No.: HY-150625
CAS No.: 923140-39-0
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SARS-CoV-2 nsp13-IN-4 (C4 (d)) is a potent and selective nsp13 helicase small-molecule inhibitor and inhibit the ssDNA+ ATPase activity of nsp13 with an IC50 value of 57 μM. SARS-CoV-2 nsp13-IN-4 is agentlike molecule with molecular weight of less than 450Da and can provide a broad-spectrum antiviral effect .
Cat. No.: HY-E70582
Target:
Research Areas:
E.coli tRNA adenosine deaminase is derived from E.coli and is an adenine deaminase that can deaminate adenine in single-stranded RNA (ssRNA, mainly the loop region within tRNA) or double-stranded RNA (dsRNA), but has no deamination activity on DNA. E.coli tRNA adenosine deaminase is a protein-modified mutant of adenine deaminase, which can efficiently deaminate adenine in ssDNA and can be applied to adenine base editors (ABE) and RNA m6A methylation sequencing .
Cat. No.: HY-D3082
CAS No.: 2222720-58-1
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Probe L is an AIE-based dual-sensing fluorescent probe for the detection of Zn 2+ and single-stranded DNA (ssDNA). Coordination of Probe L with Zn 2+ restricts intramolecular rotation and triggers ESIPT, turning on fluorescence at 490 nm. Upon further binding of the Probe L-Zn 2+ complex to ssDNA, enhanced emission is generated at 550 nm. Ex/Em = 365/490 nm (Zn 2+); Ex/Em = 365/550 nm (ssDNA) .
Cat. No.: HY-101879R
CAS No.: 65-61-2
Cat. No.: HY-185185
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S58 aptamer is a ssDNA aptamer targeting transforming growth factor-beta receptor II (TGF-β RII). S58 aptamer inhibits the TGF-β RII interaction with TGF-β. S58 aptamer effectively improves glaucoma filtration surgery (GFS) surgical outcomes by activating the intracellular antioxidant defense PI3K/Akt/Nrf2 signaling pathway .
Cat. No.: HY-157264
CAS No.: 1472655-21-2
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dTPT3TP is a non-natural nucleoside triphosphate. dTPT3TP can be used by TdT to extend ssDNA primers .
Cat. No.: HY-E70608
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PcrA spirase is an ATP-driven 3′ to 5′ helicase responsible for unwinding double-stranded DNA (dsDNA). PcrA spirase binds to dsDNA and unwinds it into two single-stranded DNAs (ssDNA).
Cat. No.: HY-D0922A
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Cy3.5 acetate is a cyanine-based red fluorescent dye (Ex/Em ≈ 560-581/600-612 nm). After covalent conjugation with proteins, Cy3.5 acetate exhibits extraordinary fluorescence enhancement with minimal quenching even at high labeling ratios. Cy3.5 acetate can form a FRET dye pair with Cy5.5, which maintains stable FRET efficiency in various biochemical buffers and deoxygenated systems. Cy3.5 acetate is applicable to studies related to fluorescent labeling of antibodies/proteins, single-molecule FRET imaging of double-stranded DNA and nucleosomes, SPION functionalization, in vivo tracing, and other relevant research .
Cat. No.: HY-P703336
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RBM38; DJ800J21.2; Prev. RNPC1; Seb4B; HSRNASEB; RNA-Binding Region (RNP1, RRM) Containing 1; RNA-Binding Region-Containing Protein 1; RNA-Binding Motif Protein 38; ssDNA-Binding Protein SEB4; CLL-Associated Antigen KW-5; RNA-Binding Protein 38; SEB4; RNA
Species:
Human
Source:
E. coli
Cat. No.: HY-D3362
Research Areas:
RL420 is an RNA-selective fluorescent covalent probe that binds covalently to the 2′-hydroxyl group of RNA via an acylimidazole-mediated reaction. RL420 has excitation/emission wavelengths of 420/452 nm, exhibits a 150-fold selectivity for RNA over DNA, and shows high labeling efficiency. RL420 can be used in studies related to in vitro RNA labeling, gel imaging, and blue fluorescent imaging of RNA in fixed cells (e.g., nucleoli) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
