61 Results for "

Psd

" in MedChemExpress (MCE) Product Catalog:
Products (61)

61 Results for "Psd" in MCE Product Catalog:

Cat. No.: HY-RS11274
Research Areas:  

Others

PSD3 Human Pre-designed siRNA Set A contains three designed siRNAs for PSD3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS11275
Research Areas:  

Others

PSD4 Human Pre-designed siRNA Set A contains three designed siRNAs for PSD4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS10573
Research Areas:  

Others

PISD Human Pre-designed siRNA Set A contains three designed siRNAs for PISD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P2307
CAS No.: 847829-41-8
Target:  

iGluR NO Synthase

Research Areas:  

Neurological Disease

Tat-NR2BAA is the control peptide of Tat-NR2B9c (HY-P0117), inactive. The sequence of Tat-NR2BAA is similar to Tat-NR2B9c, but it has a double-point mutation in the COOH terminal tSXV motif, making it incapable of binding PSD-95. Tat-NR2B9c is a membrane-permeant peptide and disrupts PSD-95/NMDAR binding, correlate with uncoupling NR2B- and/or NR2A-type NMDARs from PSD-95 .
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Cat. No.: HY-P2307A
Target:  

iGluR NO Synthase

Research Areas:  

Neurological Disease

Tat-NR2BAA TFA is the control peptide of Tat-NR2B9c (HY-P0117), inactive. The sequence of Tat-NR2BAA TFA is similar to Tat-NR2B9c, but it has a double-point mutation in the COOH terminal tSXV motif, making it incapable of binding PSD-95. Tat-NR2B9c is a membrane-permeant peptide and disrupts PSD-95/NMDAR binding, correlate with uncoupling NR2B- and/or NR2A-type NMDARs from PSD-95 .
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Cat. No.: HY-P1195A
Target:  

iGluR

Research Areas:  

Neurological Disease

PDZ1 Domain inhibitor peptide TFA, a cyclic peptide, incorporates a β-Ala lactam side chain linker and targets the PDZ1 domains of the postsynaptic density protein 95 (PSD-95). PDZ1 Domain inhibitor peptide TFA disrupts the GluR6/PSD-95 interaction and is very efficient in competing against the C terminus of GluR6 for the PDZ1 domain .
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Cat. No.: HY-P10212
CAS No.: 1786434-31-8
Synonyms: UCCB01-125
Target:  

iGluR

Research Areas:  

Neurological Disease

AVLX-125 (UCCB01-125) is a PSD-95 and PDZ domain inhibitor with Kd value of 10 nM. AVLX-125 can be used in the study of inflammatory pain .
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Cat. No.: HY-155355
Target:  

iGluR

Research Areas:  

Neurological Disease

LY836 is an orally active neuroprotective agent. LY836 significantly blocks PSD95-nNOS association in cortical neurons. LY836 can be used in study ischemic stroke .
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Cat. No.: HY-P10401
TAT-GluR6-9c is a GluR6-PSD95 interaction blocker. By regulating the GluR6 mediated signaling pathway, TAT-GluR6-9c inhibits the activation of JNK and phosphorylation of c-Jun, reduces the expression of Fas L and thus reduces the occurrence of apoptosis. TAT-GluR6-9c can be used to study cerebral ischemia and neuroprotective strategies .
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Cat. No.: HY-B0725R
CAS No.: 1229-29-4
Doxepin Hydrochloride (Standard) is the analytical standard of Doxepin Hydrochloride (HY-B0725). This product is intended for research and analytical applications. Doxepin Hydrochloride is an orally active, blood-brain barrier penetrant tricyclic antidepressant with multiple activities including hypnosis, sedation, analgesia and vasodilation. Doxepin Hydrochloride enhances the expression of PSD-95 and synapsin 1 via the PI3K/AKT/mTOR signaling pathway, and is metabolized to DesmethylDoxepin Hydrochloride in vivo. Doxepin Hydrochloride can be used in research related to various diseases such as depression, anxiety, obesity and atopic dermatitis .
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Cat. No.: HY-143675S
1-Palmitoyl-2-palmitoyl-sn-glycero-3-PS-d9 is the deuterium labeled 1-Palmitoyl-2-palmitoyl-sn-glycero-3-PS .
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Cat. No.: HY-167592S
CAS No.: 2936622-56-7
Synonyms: 1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero(d5)-3-phospho- L-serine sodium
17:0-20:3 PS-d5 (1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero(d5)-3-phospho- L-serine (sodium)) is deuterium labeled 17:0-20:3 PS .
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Cat. No.: HY-100458
CAS No.: 2185855-51-8
Target:  

NO Synthase

Research Areas:  

Neurological Disease

SCR-4026 is a neuroprotective agent with blood-brain barrier penetration ability. SCR-4026 exerts neuroprotective effects by disrupting the interaction between neuronal nNOS and PSD9, with an IC50 of 6.3 μM. SCR-4026 alleviates N-methyl-D-aspartate (NMDA)-induced excitotoxic damage in primary cortical neurons, and also protects neurons in the oxygen-glucose deprivation (OGD) model. SCR-4026 can reduce the cerebral infarct volume in the rat middle cerebral artery occlusion (MCAO) reperfusion model. SCR-4026 can be used for the study of stroke .
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Cat. No.: HY-175824
PSD-95/nNOS PPI-IN-1 is a inhibitor targeting the PSD-95/nNOS interaction with potential blood-brain barrier penetration. PSD-95/nNOS PPI-IN-1 binds to the PSD-95 PDZ2 domain with high affinity (Ki = 19.45 μM). PSD-95/nNOS PPI-IN-1 inhibits glutamate-induced excitotoxicity by reducing intracellular ROS levels and inhibiting apoptosis. PSD-95/nNOS PPI-IN-1 significantly reduces cerebral infarct volume in rat tMCAO models. PSD-95/nNOS PPI-IN-1 can be used for the study of acute ischemic stroke .
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Cat. No.: HY-176867
Target:  

HDAC

Research Areas:  

Neurological Disease

Rodin-B is a selective histone deacetylase (HDAC)-co-repressor of repressor element-1 silencing transcription factor (CoREST) complex inhibitor with an IC50 value of 0.50 μM for the CoREST complex, 0.27 μM for HDAC1, and 0.28 μM for HDAC2. Rodin-B increases the acetylation level of histone H3K9, upregulates the expression of neuron-related genes, thereby promoting the increase in dendritic spine density, the colocalization of synaptic proteins (SV2A and PSD95), and the improvement of hippocampal long-term potentiation (LTP), exerting synaptic protection and repair activity. Rodin-B is promising for research of neurodegenerative diseases related to synaptic dysfunction, especially Alzheimer’s disease .
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Cat. No.: HY-RS18221
Research Areas:  

Others

Psd Mouse Pre-designed siRNA Set A contains three designed siRNAs for Psd gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P84437
Synonyms: MRD62; Psd95; SAP90; SAP-90

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P84437A
Synonyms: MRD62; Psd95; SAP90; SAP-90

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-100457R
CAS No.: 866927-10-8
Research Areas:  

Neurological Disease

IC87201 (Standard) is the analytical standard of IC87201 (HY-100457). This product is intended for research and analytical applications. IC87201, an inhibitor of PSD95-nNOS protein-protein interactions, suppresses NMDAR-dependent NO and cGMP formation.
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Cat. No.: HY-P80285
Synonyms: Dlgh4, Psd95, Dlg4, Disks large homolog 4, Postsynaptic density protein 95, Synapse-associated protein 90, Psd-95, SAP-90, SAP90

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, FC, IP

Reactivity:  

Human, Mouse, Rat

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