Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
103 Results for "
K current
" in MedChemExpress (MCE) Product Catalog:
Products (103)
103 Results for "K current" in MCE Product Catalog:
Cat. No.: HY-P10358
CAS No.: 1505463-57-9
Target:
Research Areas:
Cat. No.: HY-15643
CAS No.: 154447-38-8
Target:
Research Areas:
LY303511 is a structural analogue of LY294002. LY303511 does not inhibit PI3K. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells. LY303511 reversibly blocks K + currents (IC50=64.6±9.1 μM) in MIN6 insulinoma cells.
Target:
Research Areas:
AZSMO-23 is a potent hERG K + channel activator. AZSMO-23 activats WT hERG pre-pulse and tail current with EC50 values of 28.6, 11.2 µM, respectively. AZSMO-23 has the potential for the research of long QT syndrome .
Target:
Research Areas:
PG01 is a potent CFTR Cl - channel potentiator. PG01 can correct gating defects of CFTR mutants, is effective on b>E193K, G970R and G551D (CFTR mutants) with Kd values of 0.22 μM, 0.45 μM and 1.94 μM, respectively. PG01 is also effective on ΔF508 (Ka of 0.3 μM). PG01 increases ΔF508-CFTR Cl - current after adding Forskolin .
Cat. No.: HY-W011235S
CAS No.: 1188265-34-0
Cat. No.: HY-P0249A
CAS No.: 159237-99-7
Target:
Research Areas:
Cat. No.: HY-100783A
CAS No.: 53552-05-9
Target:
Research Areas:
(+)-Bicuculline methobromide is a potent GABAA blocker. (+)-Bicuculline methobromide alters membrane properties and firing pattern. (+)-Bicuculline methobromide reduces the Apamin-sensitive afterhyperpolarization, while Apamin is a toxin isolated from bee venom to block small conductance Ca 2+ -activated K + channels. (+)-Bicuculline methobromide facilitates burst firing via blocking apamin-sensitive Ca 2+ -activated K + current .
Target:
Research Areas:
Prenylamine lactate is a calcium-modulating protein (CaM) antagonist that inhibits CaM-dependent enzymes and can slowly relax smooth muscle preparations. The effect of Prenylamine lactate on smooth muscle is not inhibited by the calcium agonist Bay K 8644 (HY-10588). Reports suggest that under low heart rate conditions, Prenylamine seems to enhance voltage-dependent transmembrane calcium currents .
Cat. No.: HY-135556AS
CAS No.: 1185132-92-6
Cat. No.: HY-P3071A
Synonyms: Stichodactyla helianthus neurotoxin TFA
Target:
Research Areas:
Cat. No.: HY-P1426
Target:
Research Areas:
Cat. No.: HY-P5921
CAS No.: 152618-71-8
Synonyms: TsTx-Kα
Target:
Research Areas:
Cat. No.: HY-119211
CAS No.: 72456-63-4
Target:
Research Areas:
LY 97241 accelerates the apparent rate of inactivation of transient outward K current. LY 97241 is an antiarrhythmic drug .
Cat. No.: HY-117528
CAS No.: 138490-53-6
Target:
Research Areas:
WAY-123398 is a class III antiarrhythmic agent. WAY-123398 is a selective blocker of the delayed rectifier K + current .
Cat. No.: HY-P0249
CAS No.: 64190-70-1
Target:
Research Areas:
Target:
Research Areas:
N-Bromoacetamide can irreversibly remove sodium channel inactivation in the cytoplasmic face of the membrane, also decreasing K current rapid inactivation .
Cat. No.: HY-106855
CAS No.: 123955-10-2
Synonyms: H 234/09
Target:
Research Areas:
Almokalant is a class III antiarrhythmic agent, acts as a potassium channel blocker, and inhibits a specific component (Ikr) of the time-dependent delayed rectifier K + current.
Cat. No.: HY-P0249B
CAS No.: 152165-14-5
Target:
Research Areas:
Cat. No.: HY-110015
CAS No.: 163163-24-4
Target:
Research Areas:
(-)-Chromanol 293B is a potent and selective inhibitor of the slow component of delayed rectifier K + current (IKs). (-)-Chromanol 293B can be used for the research of antiarrhythmic .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
