154447-38-8
Chemical Structure
LY 303511
- CAS No.: 154447-38-8
- Formula:C19H18N2O2
- Molecular Weight:306.36
IUPAC Name: 8-phenyl-2-(piperazin-1-yl)-4H-chromen-4-one
InChIKey: NGAGMBNBKCDCDJ-UHFFFAOYSA-N
SMILES: O=C1C=C(N2CCNCC2)OC3=C(C4=CC=CC=C4)C=CC=C13
Biological Activity: LY303511 is a structural analogue of LY294002. LY303511 does not inhibit PI3K. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells. LY303511 reversibly blocks K+ currents (IC50=64.6±9.1 μM) in MIN6 insulinoma cells.
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LY 303511 | LY303511 is a structural analogue of LY294002. LY303511 does not inhibit PI3K. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells. LY303511 reversibly blocks K+ currents (IC50=64.6±9.1 μM) in MIN6 insulinoma cells. | |||||||||||||||||||||
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Keywords