2. Membrane Transporter/Ion Channel
  3. Potassium Channel Sodium Channel
  4. N-Bromoacetamide

N-Bromoacetamide can irreversibly remove sodium channel inactivation in the cytoplasmic face of the membrane, also decreasing K current rapid inactivation.

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N-Bromoacetamide Chemical Structure

N-Bromoacetamide Chemical Structure

CAS No. : 79-15-2

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N-Bromoacetamide Related Antibodies

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Description

N-Bromoacetamide can irreversibly remove sodium channel inactivation in the cytoplasmic face of the membrane, also decreasing K current rapid inactivation[1][2].

IC50 & Target

Sodium channel, Potassium channel[1][2]
Molecular Weight

137.96

Formula

C2H4BrNO
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

CC(NBr)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (724.85 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.2485 mL 36.2424 mL 72.4848 mL
5 mM 1.4497 mL 7.2485 mL 14.4970 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

V1

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C2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (246 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 7.2485 mL 36.2424 mL 72.4848 mL 181.2119 mL
5 mM 1.4497 mL 7.2485 mL 14.4970 mL 36.2424 mL
10 mM 0.7248 mL 3.6242 mL 7.2485 mL 18.1212 mL
15 mM 0.4832 mL 2.4162 mL 4.8323 mL 12.0808 mL
20 mM 0.3624 mL 1.8121 mL 3.6242 mL 9.0606 mL
25 mM 0.2899 mL 1.4497 mL 2.8994 mL 7.2485 mL
30 mM 0.2416 mL 1.2081 mL 2.4162 mL 6.0404 mL
40 mM 0.1812 mL 0.9061 mL 1.8121 mL 4.5303 mL
50 mM 0.1450 mL 0.7248 mL 1.4497 mL 3.6242 mL
60 mM 0.1208 mL 0.6040 mL 1.2081 mL 3.0202 mL
80 mM 0.0906 mL 0.4530 mL 0.9061 mL 2.2651 mL
100 mM 0.0725 mL 0.3624 mL 0.7248 mL 1.8121 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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N-Bromoacetamide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Bromoacetamide79-15-2Potassium ChannelSodium ChannelKcsANa channelsNa+ channelsNaKIon channelInactivationInhibitorinhibitorinhibit

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