1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. Almokalant

Almokalant (Synonyms: H 234​/09)

Cat. No.: HY-106855
Handling Instructions

Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker, and inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current.

For research use only. We do not sell to patients.

Almokalant Chemical Structure

Almokalant Chemical Structure

CAS No. : 123955-10-2

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Description

Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker, and inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current.

IC50 & Target

Potassium channel[1]

In Vitro

Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker, and inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current[1].

In Vivo

Almokalant (125 μmol/kg, p.o.) induces cardiovascular defects, orofacial clefts, and tail defects in pregnant rats, after administration on Day 11. Almokalant also causes in pregnant rats[1].

Molecular Weight

352.49

Formula

C₁₈H₂₈N₂O₃S

CAS No.

123955-10-2

SMILES

CCCS(CCCN(CC)CC(O)COC1=CC=C(C#N)C=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Almokalant
Cat. No.:
HY-106855
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