(-)-Chromanol 293B
(-)-Chromanol 293B is a potent and selective inhibitor of the slow component of delayed rectifier K+ current (IKs). (-)-Chromanol 293B can be used for the research of antiarrhythmic.
For research use only. We do not sell to patients.
- CAS No.: 163163-24-4
- Formula: C15H20N2O4S
- Molecular Weight:324.40
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
IKs[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Oocyte | IC50 |
5 μM
Compound: (3R,4S)-enantiomer of 21
|
Inhibition of guinea pig Iks potassium channel expressed in Xenopus oocytes
Inhibition of guinea pig Iks potassium channel expressed in Xenopus oocytes
|
[PMID: 14998318] |
| Oocyte | IC50 |
5 μM
Compound: 1a
|
Inhibition of human IKs-channel expressed in Xenopus oocytes,(Experiment 1)
Inhibition of human IKs-channel expressed in Xenopus oocytes,(Experiment 1)
|
[PMID: 11689069] |
(-)-Chromanol 293B selectively inhibits the KvLQT11＋minK ion channel complex[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 163163-24-4
-
Molecular Weight 324.40
-
Formula C15H20N2O4S
-
SMILES
CCS(=O)(N([C@@H]1[C@@H](O)C(C)(C)OC2=CC=C(C#N)C=C12)C)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(-)-Chromanol 293B Related Classifications
HY-110015 Related Classifications
Powered by Bioz