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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
260 Results for "
Mer
" in MedChemExpress (MCE) Product Catalog:
Products (260)
260 Results for "Mer" in MCE Product Catalog:
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DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205b free base also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205b free base can inhibit cell migration in vitro and tumor growth in vivo .
Cat. No.: HY-160230
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ssRNA41 sodium is a 20-mer phosphothioate protected single-stranded RNA oligonucleotide. It derives from ssRNA40 by replacement of all U nucleotides with adenosine. ssRNA41 sodium is unable to induce the production of type IFNs, and therefore can be used as a negative control for ssRNA40 .
Cat. No.: HY-P991551
CAS No.: 1656248-21-3
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Cat. No.: HY-149906C
Purity: 98.83%
Synonyms: GEM91 sodium
Trecovirsen sodium is a 25-mer antisense phosphorothioate oligonucleotide targeted at the gag site of the HIV gene.
Cat. No.: HY-P2468
CAS No.: 331762-68-6
Synonyms: BADBH3 103-127 (human); BADBH3 (human)
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Cat. No.: HY-114426
CAS No.: 835872-35-0
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AT-1002, a 6-mer synthetic peptide , is a tight junction regulator and absorption enhancer .
0 Images
DNA, d(P-thio)(T-C-A-T-C-A-T-T-T-T-G-T-C-A-T-T-T-T-G-T-C-A-T-T), sodium salt
Cat. No.: HY-158822A
Purity: 99.35%
Cat. No.: HY-162645
CAS No.: 3029897-97-7
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BPR5K230 is a dual inhibitor for the receptor tyrosine kinase MER and AXL, with IC50 of 4.1 nM and 9.2 nM. BPR5K230 inhibits the proliferation of Ba/F3-MER with IC50 of 5 nM. BPR5K230 exhibits good pharmacokinetic characteristics in mice, exhibits anti-inflammatory and antitumor against 4T1, MDA-MB-231, MC38 and Hepa1?6 in mouse models .
Cat. No.: HY-P2499A
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Cat. No.: HY-153012
CAS No.: 2394874-60-1
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Axl/Mer-IN-1 (Compound 1) is an Axl/Mer receptor tyrosine kinase (Axl/Mer RTK) and CSF1R inhibitor with Kds of <0.1 μM .
Cat. No.: HY-16961A
CAS No.: 2244864-88-6
Synonyms: MGCD516 malate; MG-516 malate
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Sitravatinib malate (MGCD516 malate) is an orally bioavailable receptor tyrosine kinase (RTK) inhibitor with IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively . Sitravatinib malate shows potent single-agent antitumor efficacy and enhances the activity of PD-1 blockade through promoting an antitumor immune microenvironment .
Cat. No.: HY-P10935
CAS No.: 1860001-61-1
Synonyms: 5-MP
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Cat. No.: HY-N16422
CAS No.: 159121-98-9
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Cat. No.: HY-P3129
CAS No.: 145019-94-9
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Cat. No.: HY-172553
CAS No.: 3090710-48-5
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AS-0017445 is an inhibitor targeting the main protease of both the current coronavirus and the virus that caused the Middle East Respiratory Syndrome (MERS) outbreak. AS-0017445 inhibits the viral protein processing in host cells and thus prevents viral replication .
Cat. No.: HY-P9806
Synonyms: MerS-D12; MerS Antibody-D12
Cat. No.: HY-177610
CAS No.: 151356-08-0
Synonyms: ISIS 2105
Afovirsen is a 20-mer phosphorothioate oligonucleotide. It is complementary to the mRNA sequence for the translation initiation codon of the E2 protein vital to replication of HPV types 6 and 11.
Cat. No.: HY-153277
CAS No.: 2394874-63-4
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Axl/Mer/CSF1R-IN-2 (Comp 4) is a Axl, Mer and CSF1R inhibitor .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
