835872-35-0
835872-35-0
Chemical Structure
AT-1002
- CAS No.: 835872-35-0
- Formula:C32H53N9O7S
- Molecular Weight:707.88
IUPAC Name: L-phenylalanyl-L-cysteinyl-L-isoleucylglycyl-L-arginyl-L-leucine
InChIKey: LADIUXCZKYKVRR-PSEZLDIXSA-N
SMILES: N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CS)C(N[C@@H]([C@H](CC)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O
Biological Activity: AT-1002, a 6-mer synthetic peptide[1], is a tight junction regulator and absorption enhancer[2].
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AT-1002 | AT-1002, a 6-mer synthetic peptide, is a tight junction regulator and absorption enhancer. | |||||||||||||||||||||
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References
- [1]. Li M, et al. Structure-activity relationship studies of permeability modulating peptide AT-1002. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4584-6. [Content Brief]
- [2]. Gopalakrishnan S, et al. Mechanism of action of ZOT-derived peptide AT-1002, a tight junction regulator and absorption enhancer. Int J Pharm. 2009 Jan 5;365(1-2):121-30. [Content Brief]
Keywords
