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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
72 Results for "
NFAT
" in MedChemExpress (MCE) Product Catalog:
Products (72)
72 Results for "NFAT" in MCE Product Catalog:
YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation. YZ129-induced GBM cell-cycle arrest at the G2/M phase promotes apoptosis and inhibited tumor cell proliferation and migration .
Cat. No.: HY-RS24070
Target:
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Nfat5 Rat Pre-designed siRNA Set A contains three designed siRNAs for Nfat5 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-112816A
CAS No.: 1049704-17-7
MA242 free base is a specific dual inhibitor of MDM2 and NFAT1. MA242 free base directly binds both MDM2 and NFAT1 with high affinity, induces their protein degradation, and inhibits NFAT1-mediated transcription of MDM2. MA242 free base induces apoptosis in pancreatic cancer cell lines regardless of p53 status .
Cat. No.: HY-N16431
CAS No.: 165133-85-7
Category:
Cat. No.: HY-B0579S2
Synonyms: Cyclosporine A acetate-d4; Ciclosporin A acetate-d4; CsA acetate-d4
Cat. No.: HY-B0579S5
Synonyms: Cyclosporine A-d12; Ciclosporin A-d12; CsA-d12
Cat. No.: HY-RS09237
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NFAT5 Human Pre-designed siRNA Set A contains three designed siRNAs for NFAT5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17610
Target:
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Nfat5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nfat5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-161389
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Research Areas:
SP-alkyne (compound 8) suppresses IL-2 production and AP-1 and NFAT reporters .
Cat. No.: HY-161390
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SPC-alkyne (compound 9) is an alkynyl derivative. SPC-alkyne suppresses IL-2 production and AP-1 and NFAT reporters .
Cat. No.: HY-160840
CAS No.: 3027246-93-8
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SPB-AAD is a BFPX probe. SPB-AAD has covalent capture of in vitro assembled MEF2/DNA and NFAT1/DNA complexes .
Cat. No.: HY-14789R
CAS No.: 834153-87-6
Synonyms: NBI-56418 (Standard)
Research Areas:
(R)-Elagolix (Standard) is the analytical standard of (R)-Elagolix. This product is intended for research and analytical applications. Elagolix is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (KD = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .
Cat. No.: HY-W751574
Synonyms: NBI-56418-d6 sodium
Cat. No.: HY-B0579S1
CAS No.: 222295-76-3
Synonyms: Cyclosporine A-d3; Ciclosporin A-d3; CsA-d3
Cat. No.: HY-108544R
CAS No.: 3519-82-2
Synonyms: Triptycene-1,4-quinone (Standard)
Research Areas:
INCA-6 (Standard) is the analytical standard of INCA-6 (HY-108544). This product is intended for research and analytical applications. INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor. INCA-6 specifically blocks targeting of NFAT(P) substrate to the calcineurin (CN) phosphatase site and is an effective inhibitor of CN-NFAT signaling .
Cat. No.: HY-183955
CAS No.: 2041071-54-7
Research Areas:
GNF7156 is a DYRK1A/GSK3B inhibitor, IC50 values of 100 nM for DYRK1A and 40 nM for GSK3B. GNF7156 inhibits DYRK1A and GSK3B kinase activity and induces NFAT nuclear retention. GNF7156 stimulates beta-cell cycle entry and division and maintains insulin secretory capacity. GNF7156 can be used for the research of type 1 diabetes, and type 2 diabetes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
