Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
72 Results for "
NFAT
" in MedChemExpress (MCE) Product Catalog:
Products (72)
72 Results for "NFAT" in MCE Product Catalog:
Cat. No.: HY-P81644A
Synonyms: NFATC1; NFAT2; NFATC; Nuclear factor of activated T-cells; cytoplasmic 1; NF-ATc1; NFATc1; NFAT transcription complex cytosolic component; NF-ATc; NFATc
Cat. No.: HY-P992352
Cat. No.: HY-115633
CAS No.: 2323071-30-1
Research Areas:
Elagolix is an orally active, highly effective, selective and non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (KD = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis .
Cat. No.: HY-P80243
Synonyms: cytoplasmic 1 antibody;
MGC138448 antibody;
NF ATc antibody;
NF ATc1 antibody;
NF-ATc antibody;
NF-ATc1 antibody;
NF-ATc1.2 antibody;
NFAC1_HUMAN antibody;
NFAT 2 antibody;
NFAT transcription complex cytosolic component antibody;
NFATC 1 antibody;
NFATc antibody;
NFATc1 antibody;
Nuclear factor of activated T cells cytoplasmic 1 antibody;
Nuclear factor of activated T cells cytoplasmic calcineurin dependent 1 antibody;
Nuclear factor of activated T cells cytosolic component 1 antibody;
nuclear factor of activated T-cells 'c' antibody;
Nuclear factor of activated T-cells antibody
Cat. No.: HY-115633S
CAS No.: 2455524-81-7
Cat. No.: HY-N17413
CAS No.: 1357469-94-3
Cat. No.: HY-184969
Research Areas:
NUCC-0227579 is a VHL-recruiting PROTAC degrader targeting CD73, with a DC50 of 0.32 μM. NUCC-0227579 synergistically mediates CD73 degradation through the ubiquitin-proteasome pathway and the lysosomal pathway. NUCC-0227579 inhibits the conversion of AMP to adenosine, abrogates adenosine-mediated immunosuppression, upregulates the activities of the NF-κB and NFAT pathways, and enhances the secretion, activation and proliferation levels of IFN-γ and TNF-α. NUCC-0227579 downregulates NAD + synthesis in tumor cells, and inhibits the proliferation, migration and adhesion abilities of tumor cells under glutamine-deficient conditions. NUCC-0227579 significantly suppresses tumor growth in a humanized NSG mouse model of triple-negative breast cancer .
Cat. No.: HY-P702971
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NFATC1; Nuclear Factor Of Activated T-Cells 'C'; Nuclear Factor Of Activated T Cells 1; Nuclear Factor Of Activated T-Cells 1; NFATc; Alternative Protein NFATC1; NFAT2; NF-ATc1.2; NF-ATC; NF-ATc1; Nuclear Factor Of Activated T-Cells, Cytoplasmic, Calcineu
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P11648
CAS No.: 292851-89-9
Target:
Research Areas:
Cat. No.: HY-W097625R
CAS No.: 26964-24-9
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
