67 Results for "

TANDEM

" in MedChemExpress (MCE) Product Catalog:
Products (67)

67 Results for "TANDEM" in MCE Product Catalog:

Cat. No.: HY-183603
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

FRC-222 is a CHD1 tandem chromodomain inhibitor with a Kd of 0.15 μM and an IC50 of 0.18 μM. FRC-222 binds to the H3K4me3 binding site of CHD1 tandem chromodomain via aromatic cage interactions and extended ligand contacts. FRC-222 can be used for the research of prostate cancer[1].
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Cat. No.: HY-183602
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

FRC-303 is a CHD1 inhibitor with a Kd of 0.14 μM and an IC50 of 0.18 μM. FRC-303 binds to the H3K4me3 binding site of CHD1 tandem chromodomain, forms aromatic cage interactions and extended ligand contacts, acts as a methyl-lysine mimic, and occupies natural peptide ligand-binding regions. FRC-303 can be used for the research of prostate cancer .
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Cat. No.: HY-180588
Target:  

ADC Linkers

Research Areas:  

Cancer

RED-601 is a tandem-cleavable ADC linker. RED-601 can be used for synthesis of ADCs, such as XB010 .
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Cat. No.: HY-D3561
Activated PE-Texas Red is a pre-activated dual-color tandem dye for simple and efficient labeling of antibodies, streptavidin, or other proteins. It can be used in experiments such as flow cytometry (Ex/Em = 565/600 nm).
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Cat. No.: HY-D3327
PE-AF700 is a tandem fluorescent dye used for flow cytometry, consisting of the donor phycoerythrin (PE) and the acceptor Alexa Fluor 700 (AF700) (Ex/Em = 488 nm/715 nm) .
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Cat. No.: HY-D3560
Activated APC-AF750 is a pre-activated dual-color tandem dye for simple and efficient labeling of antibodies or other thiol-containing proteins. It can be used in experiments such as flow cytometry (Ex/Em = 565/780 nm).
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Cat. No.: HY-D3562
Activated RPE-Cy5 is a pre-activated dual-color tandem dye for simple and efficient labeling of antibodies or other thiol-containing proteins. It can be used in experiments such as flow cytometry (Ex/Em = 565/667 nm).
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Cat. No.: HY-D3563
Activated RPE-Cy5.5 is a pre-activated dual-color tandem dye for simple and efficient labeling of antibodies or other thiol-containing proteins, suitable for experiments such as flow cytometry (Ex/Em = 565/695 nm).
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Cat. No.: HY-D3564
Activated RPE-Cy7 is a pre-activated dual-color tandem dye for simple and efficient labeling of antibodies or other thiol-containing proteins. It can be used in experiments such as flow cytometry (Ex/Em = 565/782 nm).
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Cat. No.: HY-D3320
APC-AF700 is a tandem fluorochrome conjugate for flow cytometry. APC-AF700 can be incorporated into 10-color and 12-color flow cytometry antibody panels (Ex/Em = 633/715 nm) .
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Cat. No.: HY-113005AR
Glutarylcarnitine (lithium) (Standard) is the analytical standard of Glutarylcarnitine (lithium). This product is intended for research and analytical applications. Glutarylcarnitine lithium is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes .
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Cat. No.: HY-127151
CAS No.: 861655-73-4
Synonyms: Levophencynonate hydrochloride
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

Levophencynonate is a muscarinic receptor antagonist with anticholinergic activity. The biological activity of levophencynonate makes it a key target for the determination of its concentration in human plasma in medical research. Levophencynonate was analyzed by high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) and showed good specificity and linearity .
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Cat. No.: HY-135543
CAS No.: 230313-75-4
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

Levophencynonate is a muscarinic receptor antagonist with anticholinergic activity. The biological activity of levophencynonate makes it a key target for the determination of its concentration in human plasma in medical research. Levophencynonate was analyzed by high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) and showed good specificity and linearity .
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Cat. No.: HY-D3328
APC-Cy5.5 is a tandem dye widely used in flow cytometry. It consists of the energy donor allophycocyanin (APC) and the energy acceptor Cy5.5, and operates via the fluorescence resonance energy transfer mechanism (Ex/Em = 650 nm/690 nm) .
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Cat. No.: HY-D3330
APC-Cy7 is an APC-tandem fluorochrome (allophycocyanin-cyanine 7) and degradable fluorochrome, with maximum absorption at ~650 nm, peak emission at 767 nm when excited by a 633 nm red laser, and cell-dependent degradation. APC-Cy7 undergoes time-dependent degradation (decoupling) when bound to peripheral blood leukocytes, leading to nonspecific APC channel signal, with degradation cell type-dependent. APC-Cy7 shows reduced degradation when immunolabeled cells have inhibited metabolic activity or are incubated with vitamin C. APC-Cy7 serves as a tandem fluorochrome in multiparametric flow cytometry for detection of leukocyte surface proteins when conjugated to specific antibodies (Ex/Em = 650 nm/778 nm) .
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Cat. No.: HY-D3260
PerCP-Cy5.5 is a tandem fluorescent dye composed of a polydinoflavin-chlorophyll protein complex (PerCP) coupled with the anthocyanin dye Cy5.5. PerCP-Cy5.5 is widely used in multicolor flow cytometry analysis (Ex/Em = 482/677-695 nm).
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Cat. No.: HY-110026R
CAS No.: 34823-86-4
Research Areas:  

Cancer

GTP-14564 (Standard) is the analytical standard of GTP-14564 (HY-110026). This product is intended for research and analytical applications. GTP-14564 is a tyrosine Kinase inhibitor targeting to internal tandem duplication (ITD) and FLT3. GTP-14564 inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells .
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Cat. No.: HY-P11759
Target:  

Drug Derivative

Research Areas:  

Cancer

Myr-transportan-Cys is a derivative of the cell-penetrating peptide Transportan (HY-P1732), and its conjugated myristoyl group (Myr) enhances the interaction between the peptide and cell membranes. Myr-transportan-Cys integrates three key delivery functions: nucleic acid condensation, cell penetration, and endosomal escape. Myr-transportan-Cys can form immunostimulatory tandem peptide nanocomplexes (iTPNCs) for encapsulating and delivering immunostimulatory oligonucleotide cargos to tumors .
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Cat. No.: HY-L119
337 compounds

Potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms. There are four major classes of K channels: voltage-gated potassium channel, calcium-activated potassium channel, inwardly rectifying potassium channel and tandem pore domain potassium channel. There is growing evidence that dysfunction in potassium channels correlates with several diseases, such as chronic hypertension, diabetes, hypercholesterolemia and atherosclerosis, etc.

MCE Potassium Channel Compound Library consists of 337 potassium channel inhibitor and activators, which is a useful tool to discover drugs for cardiovascular diseases and potassium channel research.

Cat. No.: HY-D3277
PE-VF594 is a high-brightness fluorescent dye used in flow cytometry, primarily for labeling antibodies or streptavidin to help identify specific cell subpopulations. PE-VF594 is a tandem dye composed of two covalently linked fluorescent groups: one is phycoerythrin (PE), responsible for absorbing laser energy; the other is the receptor molecule VF594. Energy is transferred from PE to VF594 via fluorescence resonance energy transfer (FRET) mechanism (Ex/Em = 450-500 nm/614 nm) .
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