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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
80 Results for "
methotrexate-
" in MedChemExpress (MCE) Product Catalog:
Products (80)
80 Results for "methotrexate-" in MCE Product Catalog:
Cat. No.: HY-135120
CAS No.: 66147-29-3
Synonyms: methotrexate α-Methyl Ester
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Methotrexate impurity 5 (Methotrexate α-Methyl Ester) is an impurity of Methotrexate.
Cat. No.: HY-137359
CAS No.: 34378-65-9
Synonyms: methotrexate impurity 10
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Methotrexate impurity 6 (Methotrexate impurity 10) is an impurity of Methotrexate.
Cat. No.: HY-122416
CAS No.: 68236-11-3
Synonyms: Lonchocarpol A; Senegalensin
Category:
Erythrinasenegalensis DC. Metabolic Disease Plants Moraceae Flavonoids Leguminosae Humulus lupulus L. Flavonones Phenols Polyphenols Disease Research Fields Cancer
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Category:
Cat. No.: HY-W745173
Cat. No.: HY-Z15986
CAS No.: 43170-88-3
Target:
Methotrexate diethyl ester is a potent DHFR inhibitor. Methotrexate diethyl ester can be used in the research of T.cruzi infection and leukemia .
Cat. No.: HY-Z8268
CAS No.: 52980-68-4
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Methotrexate impurity 7 is an impurity of Methotrexate.
Cat. No.: HY-14519C
CAS No.: 51865-79-3
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Methotrexate impurity 4 is an impurity of Methotrexate.
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Methotrexate impurity 2 is an impurity of Methotrexate.
Cat. No.: HY-Z19605
CAS No.: 70844-48-3
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Methotrexate impurity 1 is an impurity of Methotrexate.
Cat. No.: HY-115850
CAS No.: 80407-73-4
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Ornithine-methotrexate is an active compound.
Cat. No.: HY-135202
CAS No.: 83160-47-8
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Chloromethylketone methotrexate is an active compound.
Cat. No.: HY-W743130
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Methotrexate impurity 3 (Metfol-B) is an impurity of Methotrexate.
Cat. No.: HY-137357
CAS No.: 66147-31-7
Synonyms: NSC 305986; γ-MBMTX
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5-Monobutyl methotrexate (NSC 305986; γ-MBMTX) is a dihydrofolate reductase (DHFR) inhibitor and esterase substrate. 5-Monobutyl methotrexate is hydrolyzed by esterases to produce methotrexate. In rhesus monkeys, 5-Monobutyl methotrexate clears more slowly from cerebrospinal fluid than from serum, and its serum protein binding rate exceeds 99%. At the same dose rate, 5-Monobutyl methotrexate achieves cerebrospinal fluid concentrations comparable to those of Methotrexate (HY-14519), and exhibits activity against Methotrexate-resistant cells (with transport defects) that is comparable to that against sensitive parental cells. 5-Monobutyl methotrexate can be used in studies related to Methotrexate-resistant tumors .
Cat. No.: HY-121151S2
Synonyms: (±)-Amethopterin-13C,d3 disodium; (±)-CL14377-13C,d3 disodium; (±)-WR19039-13C,d3 disodium
Cat. No.: HY-14519S3
Synonyms: D-(-)-Amethopterin-13C,d3 disodium; (R)-CL14377-13C,d3 disodium; (R)-WR19039-13C,d3 disodium
Cat. No.: HY-130569A
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7-Hydroxymethotrexate sodium is a major metabolite of Methotrexate (HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis .
Cat. No.: HY-121714
CAS No.: 27150-04-5
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NSC127916 (compound Ib) is a 2,6-diaminopurine analogue of Methotrexate (HY-14519) .
Cat. No.: HY-121702
CAS No.: 14866-11-6
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Dihydrohomofolic acid, an analog of dihydrofolic acid (H2F), might be effective against tumor in which resistance to methotrexate (MTX) is associated with high leveIs of H2F-reductase .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
