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Cat. No.: HY-121702

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Dihydrohomofolic acid

Dihydrohomofolic acid, an analog of dihydrofolic acid (H₂F), might be effective against tumor in which resistance to methotrexate (MTX) is associated with high leveIs of H₂F-reductase.

For research use only. We do not sell to patients.

CAS No.: 14866-11-6
Formula: C₂₀H₂₃N₇O₆
Molecular Weight:457.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

Dihydrohomofolic acid Chemical Structure

CAS No.: 14866-11-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Dihydrohomofolic acid, an analog of dihydrofolic acid (H₂F), might be effective against tumor in which resistance to methotrexate (MTX) is associated with high leveIs of H₂F-reductase^[1].

Chemical Information

CAS No. 14866-11-6
Molecular Weight 457.44
Formula C₂₀H₂₃N₇O₆
SMILES

O=C(CC[C@H](NC(C1=CC=C(C=C1)NCCC2=NC3=C(NC2)NC(N)=NC3=O)=O)C(O)=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. L C Mishra, et al. Effect of pretreatment with methotrexate on the reduction of dihydrohomofolic acid in mice. Biochem Pharmacol. 1971 Oct;20(10):2871-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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