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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
80 Results for "
methotrexate-
" in MedChemExpress (MCE) Product Catalog:
Products (80)
80 Results for "methotrexate-" in MCE Product Catalog:
Cat. No.: HY-W745177
Cat. No.: HY-165164
CAS No.: 116819-28-4
Target:
Research Areas:
Methotrexate-alpha-alanine is a prodrug for activation by enzyme-monoclonal antibody conjugates of Methotrexate (HY-14519). Methotrexate-alpha-alanine shows cytotoxicity .
Cat. No.: HY-108251R
CAS No.: 19741-14-1
Synonyms: DAMPA (Standard)
Research Areas:
Methotrexate metabolite (Standard) is the analytical standard of Methotrexate metabolite. This product is intended for research and analytical applications. Methotrexate metabolite (DAMPA), the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist that is widely used as an immunosuppressant and chemotherapeutic agent .
Cat. No.: HY-148994
CAS No.: 64801-58-7
Target:
Research Areas:
Methotrexate-γ-aspartate is a Ll210 cell dihydrofolate reductase inhibitor. Methotrexate-γ-aspartate is apparently more resistant to enzymic cleavage than is methotrexate-y-glutamate. Methotrexate-γ-aspartate can be used in antibody-targeted liposomes and is promising for research of leukemic .
Cat. No.: HY-P991641
Synonyms: LY3012218
Cat. No.: HY-W769792
Cat. No.: HY-14519S1
Purity: 99.69%
Cat. No.: HY-108251S
CAS No.: 1794780-00-9
Synonyms: DAMPA-d3
Cat. No.: HY-W654227
Cat. No.: HY-148657
CAS No.: 98457-88-6
Synonyms: NHS-methotrexate
Target:
Research Areas:
Aminopterin N-hydroxysuccinimide ester(NHS-methotrexate) is an irreversible
Methotrexate (HY-14519) influx carrier inhibitor. Aminopterin N-hydroxysuccinimide ester can be used for the research of rheumatoid arthritis and a number of cancers (such as acute lymphoblastic leukemia) .
Cat. No.: HY-121151S
Synonyms: (±)-Amethopterin-d3; (±)-CL14377-d3; (±)-WR19039-d3
Cat. No.: HY-17556B
CAS No.: 1097832-14-8
Synonyms: Leucovorin calcium hydrate
Target:
Cat. No.: HY-121256
CAS No.: 18921-73-8
Research Areas:
Chlorasquin inhibits thymidylate synthetase with an approximate Ki value of 4.9 μM. Chlorasquin is also a folate antagonist, testing the Methotrexate (HY-14519) effect. Chlorasquin binds tighter to dihydrofolate reductase at alkaline pH than does Methotrexate, which is promising for research of antipsoriatic agents .
Cat. No.: HY-130569S
Cat. No.: HY-130569S1
CAS No.: 432545-62-5
Cat. No.: HY-108807
CAS No.: 1622456-55-6
Target:
Research Areas:
Glucarpidase is an enzyme that inactivates methotrexate. Glucarpidase can be used for renal dysfunction diseases research .
Target:
Research Areas:
7-Hydroxydichloromethotrexate is a methotrexate metabolite which can be isolated from the urine of rabbits .
Cat. No.: HY-130569S2
Target:
Research Areas:
Tetrahydromethotrexate is a more potent folate antagonist than Methotrexate (HY-14519) in studies against certain bacteria (Streptococcus faecalis, Pediococcus erevisiae) and in animal models. Tetrahydromethotrexate is used in the research of cancer and autoimmune diseases .
Cat. No.: HY-167863
CAS No.: 79483-69-5
Synonyms: BW 301U isethionate; NSC 351521 isethionate
Target:
Research Areas:
Piritrexim isethionate (BW 301U isethionate) is a fat-soluble dihydrofolate reductase inhibitor with activity in the treatment of severe psoriasis. Piritrexim isethionate may be as effective as methotrexate in the treatment of severe psoriasis and may have less hepatotoxicity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
