4299-28-9
4299-28-9
Chemical Structure
Tetrahydromethotrexate
- CAS No.: 4299-28-9
- Formula:C20H26N8O5
- Molecular Weight:458.47
IUPAC Name: (4-(((2,4-diamino-5,6,7,8-tetrahydropteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamic acid
InChIKey: GLSBTKIRCIEEJO-YUZLPWPTSA-N
SMILES: O=C(CC[C@H](NC(C1=CC=C(C=C1)N(C)CC2NC3=C(N=C(N=C3NC2)N)N)=O)C(O)=O)O
Biological Activity: Tetrahydromethotrexate is a more potent folate antagonist than Methotrexate (HY-14519) in studies against certain bacteria (Streptococcus faecalis, Pediococcus erevisiae) and in animal models. Tetrahydromethotrexate is used in the research of cancer and autoimmune diseases[1].
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Tetrahydromethotrexate | Tetrahydromethotrexate is a more potent folate antagonist than Methotrexate (HY-14519) in studies against certain bacteria (Streptococcus faecalis, Pediococcus erevisiae) and in animal models. Tetrahydromethotrexate is used in the research of cancer and autoimmune diseases. | |||||||||||||||||||||
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