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Cat. No.: HY-167863

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Piritrexim isethionate

(Synonyms: BW 301U isethionate; NSC 351521 isethionate)

Piritrexim isethionate (BW 301U isethionate) is a fat-soluble dihydrofolate reductase inhibitor with activity in the treatment of severe psoriasis. Piritrexim isethionate may be as effective as methotrexate in the treatment of severe psoriasis and may have less hepatotoxicity.

For research use only. We do not sell to patients.

CAS No.: 79483-69-5
Formula: C₁₉H₂₅N₅O₆S
Molecular Weight:451.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Piritrexim isethionate Chemical Structure

CAS No.: 79483-69-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 79483-69-5
Molecular Weight 451.50
Formula C₁₉H₂₅N₅O₆S
SMILES

O=S(O)(CCO)=O.NC1=NC(N)=NC2=NC=C(CC3=CC(OC)=CC=C3OC)C(C)=C21
Synonyms

BW 301U isethionate; NSC 351521 isethionate
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. A multicentre 12-week open study of a lipid-soluble folate antagonist, piritrexim in severe psoriasis [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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