Aminopterin N-hydroxysuccinimide ester
Aminopterin N-hydroxysuccinimide ester(NHS-methotrexate) is an irreversible Methotrexate (HY-14519) influx carrier inhibitor. Aminopterin N-hydroxysuccinimide ester can be used for the research of rheumatoid arthritis and a number of cancers (such as acute lymphoblastic leukemia).
For research use only. We do not sell to patients.
- CAS No.: 98457-88-6
- Formula: C24H27N9O8
- Molecular Weight:569.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 98457-88-6
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Molecular Weight 569.53
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Formula C24H27N9O8
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SMILES
NC1=NC(N)=NC2=C1N=C(CN(C3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(O)=O)=O)C)C=N2.O=C4N(C(CC4)=O)O
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Synonyms
NHS-Methotrexate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Henderson GB, et al. Characterization of the multiple transport routes for methotrexate in L1210 cells using phthalate as a model anion substrate. J Membr Biol. 1985;85(3):263-268. [Content Brief]
[2]. Chiao JH, et al. RFC-1 gene expression regulates folate absorption in mouse small intestine. J Biol Chem. 1997;272(17):11165-11170. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Aminopterin N-hydroxysuccinimide ester Related Classifications
HY-148657 Related Classifications
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