192 Results for "

nucleoside reverse transcriptase

" in MedChemExpress (MCE) Product Catalog:
Products (192)

192 Results for "nucleoside reverse transcriptase" in MCE Product Catalog:

Cat. No.: HY-15352
CAS No.: 214287-99-7
Synonyms: DPC 083
Research Areas:  

Infection

BMS 561390 (DPC 083) is an orally available non-nucleoside reverse transcriptase inhibitor (NNRTI) with broad inhibitory effects on wild-type HIV-1 and mutant strains .
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Cat. No.: HY-156599
CAS No.: 1956373-71-9
Target:  

HIV

Research Areas:  

Infection

Bavtavirine is a potent non-nucleoside reverse transcriptase inhibitors (NNRTIs). Bavtavirine is part of highly active antitiretroviral therapy (HAART) treatment regimen. Bavtavirine can be used for HIV disease research .
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Cat. No.: HY-162461
Research Areas:  

Infection

HIV-1 inhibitor-66 is an orally active non-nucleoside reverse transcription inhibitor (NNRTI). HIV-1 inhibitor-66 shows inhibitory activity against wild-type HIV-1 reverse transcriptase with an IC50 of 40 nM .
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Cat. No.: HY-175351
Research Areas:  

Infection

HIV-1-IN-83 (Compound 18E) is a HIV-1 non-nucleoside reverse transcriptase inhibitor with an IC50 of 0.45 μM for wild-type HIV-1 non-nucleoside reverse transcriptase. HIV-1-IN-83 has potent antiviral activity against both HIV-1 wild-type and mutant strains and improves antidrug resistance for Y188L and RES056 mutant strains. HIV-1-IN-83 has no significant toxicity up to 11.088 μM .
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Cat. No.: HY-106155
CAS No.: 145514-04-1
Synonyms: DAPD
Research Areas:  

Infection

Amdoxovir (DAPD) is an orally active nucleoside reverse transcriptase inhibitor. Amdoxovir is active against wild-type and NRTl-resistant viruses. Amdoxovir is the prodrug of dioxolane guanosine. Amdoxovir can be used for research of HIV/AIDS .
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Cat. No.: HY-116154
CAS No.: 120503-45-9
Research Areas:  

Infection

Metacavir is an orally active, potent and specific nucleoside reverse transcriptase inhibitor against hepatitis B virus (HBV) with antiviral activity .
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Cat. No.: HY-N16422
CAS No.: 159121-98-9
Mer-NF5003E is a non-nucleoside reverse transcriptase inhibitor targeting HIV-1 reverse transcriptase (RT) (EC50=50 μM). Mer-NF5003E exhibits inhibitory activity against wild-type HIV-1 and multiple NNRTI-resistant strains (e.g., K103N, Y181C). Mer-NF5003E is promising for research of HIV infections .
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Cat. No.: HY-17427S
CAS No.: 2714436-53-8
Synonyms: BW1592-15N,d2
Emtricitabine- 15N,d2 is a 15N-labeled and deuterium labeled Emtricitabine. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection.
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Cat. No.: HY-118423
CAS No.: 195720-26-4
Synonyms: IQP-0410
Target:  

HIV

Research Areas:  

Inflammation/Immunology

SJ-3366 (IQP-0410) is a potent inhibitor of HIV nonnucleoside reverse transcriptase . SJ-3366 (IQP-0410) inhibits HIV at sub-nanomolar concentrations primarily through a typical non-nucleoside mechanism .
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Cat. No.: HY-178341
Research Areas:  

Infection

NNRT-IN-13 is a potent non-nucleoside reverse transcriptase (NNRT) inhibitor that directly inhibiting HIV-1 reverse transcriptase (IC₅₀ = 0.25 μM). NNRT-IN-13 exhibits excellent antiviral activity against wild-type HIV-1 (EC₅₀ = 0.0046 μM) and a broad spectrum of drug-resistant mutants. NNRT-IN-13 exhibits favorable in vivo metabolic and safety profiles. NNRT-IN-13 can be used for human immunodeficiency virus (HIV) research .
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Cat. No.: HY-14920R
CAS No.: 134379-77-4
Synonyms: reverset (Standard); d-d4FC (Standard)
Research Areas:  

Infection

Dexelvucitabine (Standard) is the analytical standard of Dexelvucitabine. This product is intended for research and analytical applications. Dexelvucitabine (Reverset; d-d4FC), a Cytidine (HY-B0158) analog, is an orally active nucleoside reverse transcriptase inhibitor. Dexelvucitabine is a powerful agent against HIV-1-resistant viruses containing a thymidine analog and/or M184V mutation in the viral polymerase. Dexelvucitabine is a 2′-Deoxycytidine antiretroviral agent .
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Cat. No.: HY-15379
CAS No.: 136816-75-6
Purity:  98.69%
Target:  

HIV

Research Areas:  

Infection

Atevirdine is a potent non-nucleoside HIV-1 reverse transcriptase inhibitor. Atevirdine inhibits non-nucleoside reverse transcriptase that leads to viral multiplication .
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Cat. No.: HY-100260
CAS No.: 7057-48-9
Synonyms: 2'3'-didehydro-2'3'-dideoxyadenosine
Target:  

HIV

Research Areas:  

Infection

beta-L-D4A is a nucleoside HIV-1 reverse transcriptase inhibitor.
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Cat. No.: HY-17423D
CAS No.: 136470-79-6
Target:  

Drug Intermediate

Research Areas:  

Others

ent-Abacavir is an enantiomer of Abacavir. Abacavir is an orally active, competitive nucleoside reverse transcriptase inhibitor .
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Cat. No.: HY-107001
CAS No.: 214287-88-4
Synonyms: (S)-DPC 961; DMP 961
Research Areas:  

Infection

DPC 961 (DMP 961) is a non-nucleoside reverse transcriptase inhibitor (NNRTI). DPC 961 is a potent and specific inhibitor of HIV-1 reverse transcriptase, which inhibits the activity of HIV-1 reverse transcriptase in a non-competitive manner, thereby preventing viral replication. DPC 961 can be used for research on AIDS .
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Cat. No.: HY-14294
CAS No.: 178979-85-6
Synonyms: S-1153
Research Areas:  

Infection

Capravirine (S-1153) is an orally active non-nucleoside reverse transcriptase inhibitor (NNRTI) with potent antiviral activity. Capravirine inhibits replication of HIV-1 strains that are resistant to nucleoside/nucleotide reverse transcriptase inhibitors and other NNRTIs. Capravirine is metabolized by the cytochrome P450 enzyme CYP3A4 .
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Cat. No.: HY-W654247
CAS No.: 2714473-70-6
Lamivudine- 13C,d2 is the deuterium labeled and 13C-labeled Lamivudine. Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS .
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Cat. No.: HY-169207
CAS No.: 3032803-00-9
Target:  

Reverse Transcriptase

Research Areas:  

Cancer

NNRT-IN-5 (compund 10d) is an orally available non-nucleoside reverse transcriptase inhibitor .
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Cat. No.: HY-B0250S
Synonyms: BCH-189-15N,d2
Lamivudine- 15N,d2 is 15N and deuterated labeled Lamivudine (HY-B0250). Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS .
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Cat. No.: HY-105491
CAS No.: 135812-34-9
Synonyms: NSC-629243
Research Areas:  

Infection

UC-38 (NSC-629243) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) with anti-HIV activity .
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