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Cat. No.: HY-169207

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NNRT-IN-5

NNRT-IN-5 (compund 10d) is an orally available non-nucleoside reverse transcriptase inhibitor.

For research use only. We do not sell to patients.

CAS No.: 3032803-00-9
Formula: C₂₇H₂₂N₈
Molecular Weight:458.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

NNRT-IN-5 Chemical Structure

CAS No.: 3032803-00-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

NNRT-IN-5 (compund 10d) is an orally available non-nucleoside reverse transcriptase inhibitor^[1].

IC₅₀ & Target

Reverse Transcriptase^[1]

Chemical Information

CAS No. 3032803-00-9
Molecular Weight 458.52
Formula C₂₇H₂₂N₈
SMILES

CC1=CC(C2=CC=NC=C2)=CC(C)=C1NC3=C(C=NC(NC4=CC=C(C=C4)C#N)=N3)C5=CNN=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Huang WJ, et al. Fragment Addition-Based Design of Heteroaromatic-Biphenyl-DAPYs as Potent and Orally Available Non-nucleoside Reverse Transcriptase Inhibitors Featuring Significantly Enhanced Safety. J Med Chem. 2024 Oct 10;67(19):17568-17584. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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