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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
136 Results for "
Non-Nucleoside Reverse Transcriptase
" in MedChemExpress (MCE) Product Catalog:
Products (136)
136 Results for "Non-Nucleoside Reverse Transcriptase" in MCE Product Catalog:
Cat. No.: HY-132508S
CAS No.: 1142096-06-7
Cat. No.: HY-10570S
CAS No.: 1051418-95-1
Cat. No.: HY-90005R
CAS No.: 269055-15-4
Synonyms: R165335 (Standard); TMC125 (Standard)
Research Areas:
Etravirine (Standard) is the analytical standard of Etravirine. This product is intended for research and analytical applications. Etravirine (R165335; TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.
Cat. No.: HY-14294
CAS No.: 178979-85-6
Synonyms: S-1153
Target:
Research Areas:
Capravirine (S-1153) is an orally active non-nucleoside reverse transcriptase inhibitor (NNRTI) with potent antiviral activity. Capravirine inhibits replication of HIV-1 strains that are resistant to nucleoside/nucleotide reverse transcriptase inhibitors and other NNRTIs. Capravirine is metabolized by the cytochrome P450 enzyme CYP3A4 .
Cat. No.: HY-126900
CAS No.: 149486-73-7
Target:
Research Areas:
HI-253 is a non-nucleoside inhibitor of HIV-1 reverse transcriptase that has demonstrated greater activity than multiple anti-HIV compounds against both resistant and sensitive HIV-1 strains.
Cat. No.: HY-121611
CAS No.: 233271-65-3
Target:
Research Areas:
HI-236 is a potent non-nucleoside inhibitor of HIV-1 reverse transcriptase.?
HI-236 inhibits HIV activity (wild type HTLVIIB IC50p24 < 0.001 μM) .
Cat. No.: HY-150769
CAS No.: 3033486-43-7
Target:
Research Areas:
ZLM-66 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTIs) with an IC50 of 41 nM for wild-type (WT) HIV-1 reverse transcriptase and an EC50 value of 13 nM for wild-type HIV-1. ZLM-66 is a Doravirine (HY-16767) analogs. ZLM-66 can be used for the research of AIDS .
Cat. No.: HY-10570S1
CAS No.: 1051419-24-9
Cat. No.: HY-10570S2
CAS No.: 1051418-86-0
Synonyms: BI-RG 587-d8; NSC 641530-d8; NVP-d8
Cat. No.: HY-W777351
CAS No.: 1189671-48-4
Synonyms: R165335-13C3; TMC125-13C3
Cat. No.: HY-147370
CAS No.: 332947-35-0
HIV-1 inhibitor-46 (compound 13d) is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor with an EC50 value of 1.425 μM. HIV-1 inhibitor-46 can be used for the research of AIDS .
Cat. No.: HY-167135
CAS No.: 214287-98-6
Target:
Research Areas:
DPC-082 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1. DPC-082 inhibits wild-type RF virus with an IC90 of 2.0 nM. DPC-082 inhibits various single and many multiple amino acid substituted HIV-1 mutant viruses .
Cat. No.: HY-172408
Target:
Research Areas:
NNRT-IN-6 (Compound 13a) is the non-nucleoside reverse transcriptase inhibitor (NNRT) for HIV-1 reverse transcriptase (HIV-1 RT) with IC50 of 0.41 μM. NNRT-IN-6 inhibits HIV-1 wildtype and mutant strains L100I, K103N, Y181C, Y188L, E138K, F227L/V106A and RES056 with EC50 of 6.2-250 nM .
Cat. No.: HY-10893
CAS No.: 175739-42-1
TNK-651 is a non-nucleoside HIV-1 reverse transcriptase inhibitor. TNK-651 exhibits inhibitory effects on both the HIV-1 SF33 strain and the NNRTI-resistant HIV-1 A17 strain. TNK-651 can be used for the study of HIV-1 infection .
Cat. No.: HY-167642
CAS No.: 500287-94-5
Synonyms: (Z)-R278474; (Z)-TMC278; (Z)-DB08864
Target:
Research Areas:
(Z)-Rilpivirine ((Z)-R278474) is the (Z)-isomer of Rilpivirine (HY-10574). Rilpivirine is an effective and selective diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). It exhibits potent antiviral activity against both wild-type HIV (EC50 = 0.4 nM) and mutant strains (EC50 = 0.1-2.0 nM) .
Cat. No.: HY-146364
CAS No.: 2132412-25-8
Target:
Cat. No.: HY-147904
CAS No.: 2459929-62-3
HIV-IN-5 (compound 5r) is a potent HIV-1 inhibitor, with an IC50 of 0.16 μM. HIV-IN-5 shows inhibition of HIV DNA-dependent DNA polymerization activity, with an IC50 of 2.18 μM. HIV-IN-5 can bind to NNIBP (NNRTIs (non-nucleoside reverse transcriptase inhibitors) binding pocket) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
