Calophyllum brasiliense auct. non Camb.
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Calophyllum brasiliense auct. non Camb. (5)
- Formula: C22H26O5
- Molecular Weight: 370.44
(-)-Calanolide B is a non-nucleoside reverse transcriptase (NNRT) inhibitor with an IC50 of 0.5 mM against HIV-1 RT. (-)-Calanolide B inhibits the replication of HIV-1 IIIb/LAV. (-)-Calanolide B is applicable to research related to HIV-1 infection.
- Formula: C22H26O5
- Molecular Weight: 370.44
Calanolide B is a HIV-1 reverse transcriptase inhibitor. Calanolide B is applicable to research related to HIV-1 infection.
- Formula: C25H26O6
- Molecular Weight: 422.47
Brasimarin B is a 4-phenylcoumarin compound found in the stem bark of Calophyllum brasiliense. Brasimarin B inhibits TPA (HY-18739)-induced EBV-EA activation in Raji cells.
- Formula: C22H28O6
- Molecular Weight: 388.45
Isoapetalic acid (compound 4) is a potent anti-HIV agent.
- Formula: C25H26O5
- Molecular Weight: 406.47
Mammea A/BA has potent activity against Trypanosoma cruzi (T. cruzi). Mammea A/BA induces mitochondrial dysfunction, reactive oxygen species (ROS) production and DNA fragmentation, and increases number of acidic vacuoles. Mammea A/BA can induce apoptosis, autophagy and necrosis. Mammea A/BA can be used for researching chagas disease.
