5224-54-4
5224-54-4
Chemical Structure
Mammea A/BA
- CAS No.: 5224-54-4
- Formula:C25H26O5
- Molecular Weight:406.47
IUPAC Name: 5,7-dihydroxy-6-(3-methylbut-2-en-1-yl)-8-(3-methylbutanoyl)-4-phenyl-2H-chromen-2-one
InChIKey: SBHOAZQBEGVQLJ-UHFFFAOYSA-N
SMILES: O=C1C=C(C2=CC=CC=C2)C3=C(O)C(C/C=C(C)\C)=C(O)C(C(CC(C)C)=O)=C3O1
Biological Activity: Mammea A/BA has potent activity against Trypanosoma cruzi (T. cruzi). Mammea A/BA induces mitochondrial dysfunction, reactive oxygen species (ROS) production and DNA fragmentation, and increases number of acidic vacuoles. Mammea A/BA can induce apoptosis, autophagy and necrosis. Mammea A/BA can be used for researching chagas disease[1].
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Mammea A/BA | Mammea A/BA has potent activity against Trypanosoma cruzi (T. cruzi). Mammea A/BA induces mitochondrial dysfunction, reactive oxygen species (ROS) production and DNA fragmentation, and increases number of acidic vacuoles. Mammea A/BA can induce apoptosis, autophagy and necrosis. Mammea A/BA can be used for researching chagas disease. | |||||||||||||||||||||
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