1074 Results for "

detect

" in MedChemExpress (MCE) Product Catalog:
Products (1074)

1074 Results for "detect" in MCE Product Catalog:

Cat. No.: HY-W142206
CAS No.: 930-60-9
Cyclopent-4-ene-1,3-dione is a potent antifungal inhibitor of chitin synthesis. Cyclopent-4-ene-1,3-dione is potently antifungal against human pathogenic Candida species (IC50 = 1-2 μM). Cyclopent-4-ene-1,3-dione is detected in feijoa cultivars with high antifungal bioactivity. Cyclopent-4-ene-1,3-dione can be used for the research of fungal infections .
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Cat. No.: HY-W750220
Target:  

β-glucuronidase

Research Areas:  

Metabolic Disease

4-Methylumbelliferyl β-D-glucuronide dihydrate is a fluorescent substrate and fluorescent probe used to detect the activity of β-D-glucuronidase. 4-Methylumbelliferyl β-D-glucuronide dihydrate also serves as a surrogate for assessing fecal coliform contamination in aquatic environments. 4-Methylumbelliferyl β-D-glucuronide dihydrate releases 4-methylumbelliferone via enzyme-mediated cleavage of the β-glycosidic bond; the latter emits fluorescence under alkaline conditions, with an excitation wavelength of 365-366 nm and an emission wavelength of 444 nm .
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Cat. No.: HY-W928283
CAS No.: 1135372-06-3
L-Hydroxyproline 7-amido-4-methylcoumarin hydrochloride is a fluorescent substrate with biological activity for enzyme activity detection. L-Hydroxyproline 7-amido-4-methylcoumarin hydrochloride is often used in biochemical research to detect reactions associated with specific enzymes. L-Hydroxyproline 7-amido-4-methylcoumarin hydrochloride helps scientists monitor the progress of reactions through its fluorescent properties. L-Hydroxyproline 7-amido-4-methylcoumarin hydrochloride has important application value in compound development and basic biological research.
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Cat. No.: HY-124329AS
CAS No.: 910292-87-4
BS3 Crosslinker-d4 disodium is the deuterated-labeled BS3 Crosslinker disodium (HY-124329A). BS3 Crosslinker disodium is a cell-impermeable NHS ester crosslinker. BS3 Crosslinker disodium "covalently locks" two spatially adjacent proteins on the surface of living cells into a covalent complex, and the dimerization/oligomerization status is determined by observing molecular weight shifts via Western blot. BS3 Crosslinker disodium can crosslink EGFR and c-MET to assist in detecting and evaluating their dimerization status. It can be used in research related to oral cancer and glioblastoma .
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Cat. No.: HY-149203A
Purity:  97.36%
Target:  

Fluorescent Dye

Research Areas:  

Others

MQA-P is a multifunctional near-infrared (NIR) fluorescent probe that simultaneously detects ONOO -, viscosity, and polarity within mitochondria. MQA-P exhibits significant response to ONOO -, λem=645 nm; and NIR channel at λem>704 nm Medium is highly sensitive to viscosity/polarity. MQA-P possesses excited-state intramolecular charge transfer (ESICT) properties that are highly sensitive to polarity by designing the N,N-dimethylamino group as the electron donor and the quinoline cation unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images .
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Cat. No.: HY-161491
1-(2-Aminoethyl)-1H-pyrazol-4-ylphosphonic acid-linker/OVA is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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Cat. No.: HY-179554
Synonyms: PI(4,5)P2-fluorescein triethylammonium
Target:  

Fluorescent Dye

Research Areas:  

Others

PtdIns-(4,5)-P2-fluorescein (PI(4,5)P2-fluorescein) triethylammonium is a fluorescently labeled phosphatidylinositol-4,5-bisphosphate, which is a marked form of an important phospholipid signaling molecule (PIP2) on the cell membrane. PtdIns-(4,5)-P2-fluorescein triethylammonium can be used to detect proteins that interact with phosphatidylinositol-4,5-bisphosphate, such as PI3K, PTEN, and PH domain proteins, etc .
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Cat. No.: HY-185843
CAS No.: 1062136-15-5
Synonyms: dFdUTP
Target:  

Drug Metabolite

Research Areas:  

Cancer

2',2'-Difluorodeoxyuridine 5'-triphosphate (dFdUTP) is the intracellular phosphorylated metabolite of dFdU (HY-138253), which in turn is the deaminated metabolite of Gemcitabine (HY-17026). 2',2'-Difluorodeoxyuridine 5'-triphosphate incorporates into DNA and RNA, contributing to Gemcitabine-associated cytotoxicity and hepatotoxicity. 2',2'-Difluorodeoxyuridine 5'-triphosphate accumulates in the liver and kidneys of mice, and is detectable in mouse plasma and urine. 2',2'-Difluorodeoxyuridine 5'-triphosphate can be used in the research of breast cancer and non-small cell lung cancer .
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Cat. No.: HY-D0002
CAS No.: 207673-94-7
Synonyms: Coumarin 120 hydrogensulfate; AMC hydrogensulfate
7-Amino-4-methylcoumarin hydrogensulfate (Coumarin 120 hydrogensulfate; AMC hydrogensulfate) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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Cat. No.: HY-D0162R
CAS No.: 2437-29-8
Synonyms: MCCK1 (Standard)
Malachite green hemioxalate (Standard) is the analytical standard of Malachite green hemioxalate (HY-D0162). This product is intended for research and analytical applications. Malachite green hemioxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate has antimicrobial activity, which is attributed to inhibition of intracellular enzymes, intercalation into DNA, and/or interaction with cellular membranes. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo.
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Cat. No.: HY-D0307
CAS No.: 642-59-1
Synonyms: Acid Red 27 free acid; Azorubin S free acid; FD & C Red Dye No. 2 free acid
Amaranth free acid (Acid Red 27 free acid; Azorubin S free acid; FD & C Red Dye No. 2 free acid) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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Cat. No.: HY-D0498
CAS No.: 13486-43-6
2-N-Ethyl-p-(6-methoxybenzothiazol-2-yl)azoanilinoethanol is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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Cat. No.: HY-D1186
CAS No.: 50663-82-6
Synonyms: 2-Aza-1,N6-ethenoadenosine
2-Aza-ε-adenosine (2-Aza-1,N6-ethenoadenosine) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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Cat. No.: HY-D1524A
CAS No.: 185503-88-2
Synonyms: 1,8-EDNAS sodium
N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid sodium (1,8-EDNAS sodium) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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Cat. No.: HY-D3047I
Target:  

Fluorescent Dye

Research Areas:  

Others

Rhodamine B-Dextran (chloride) (MW 500000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 500000. Rhodamine B-Dextran (chloride) (MW 500000) is a fluorescent dye used to track the diffusion of macromolecules in ex vivo human skin. Rhodamine B-Dextran (chloride) (MW 500000) is delivered to skin layers via the Nanopatch microneedle array, which physically disrupts the stratum corneum and dermal-epidermal junction barriers to deposit the dye directly into epidermal and dermal regions; fluorescence is detected via multiphoton microscopy, and fluorescence intensity is assumed to be roughly proportional to dye concentration .
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Cat. No.: HY-D3402
CAS No.: 3121511-18-7
Research Areas:  

Others

LHA675 is a fluorescent probe for early detection of ferroptosis. LHA675 mimics polyunsaturated lipids via a 4-phenyl-3-methylbut-2-enyl group to specifically detect highly oxidative radicals associated with ferroptosis, and releases a fluorophore after the reaction. LHA675 has excitation and emission wavelengths of 647 nm and 663-738 nm, respectively. LHA675 enables wash-free labeling of ferroptosis in living cells; the generated fluorophore localizes to mitochondria and emits deep red fluorescence. LHA675 can be used in studies related to the early detection of ferroptosis .
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Cat. No.: HY-E72100
Target:  

Cytochrome P450

Research Areas:  

Others

Human CYP2D6, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, consisting of human cytochrome P450 2D6, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP2D6 is a human cytochrome P450 subtype belonging to the CYP2 family, and also serves as a major metabolic enzyme capable of crossing the blood-brain barrier. Its expression is centered in the human liver (also detected in the brain) and exhibits high polymorphism .
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Cat. No.: HY-I0501R
CAS No.: 551-93-9
Synonyms: o-aminoacetophenone (Standard)
2'-Aminoacetophenone (Standard) is the analytical standard of 2'-Aminoacetophenone. This product is intended for research and analytical applications. 2'-Aminoacetophenone is an orally active inducer of apoptosis and respiratory biomarker. 2'-Aminoacetophenone can be used to detect Pseudomonas aeruginosa infections in the lungs of cystic fibrosis patients. 2'-Aminoacetophenone can inhibit the protein levels of LC3BII and p62 in macrophages infected with pqsA or mvfR and regulate autophagy. 2'-Aminoacetophenone can disrupt mitochondrial function by inducing oxidative stress and apoptosis signaling, leading to dysfunction in mouse skeletal muscle .
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Cat. No.: HY-P11129
CAS No.: 289905-22-2
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

MAGE-A4 (286-294) is a polypeptide derived from the 286th to 294th amino acids of the MAGE-A4 protein. MAGE-A4 (286-294) binds HLA-­A*02 with an affinity of 560.08 nM and an IC50 of 8.52 nM. MAGE-A4 (286-294) can be detected in various types of cancers (such as esophageal cancer, lung squamous cell carcinoma, bladder cancer). MAGE-A4 (286-294) can be used to produce CAR-T cells and to develop CAR-T cell therapy .
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Cat. No.: HY-P11486
NOTA-RHAU18 is a conjugate of the chelator NOTA and the peptide RHAU18. NOTA-RHAU18 can be used to synthesize the radiolabeled peptide probe [ 18F]AlF-NOTA-RHAU18. [ 18F]AlF-NOTA-RHAU18 targets mitochondrial DNA G4. [ 18F]AlF-NOTA-RHAU18 can be used to visualize and detect solid tumors in homozygous mice. [ 18F]AlF-NOTA-RHAU18 can also be used in PET imaging studies .
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