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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
124 Results for "
catecholamine
" in MedChemExpress (MCE) Product Catalog:
Products (124)
124 Results for "catecholamine" in MCE Product Catalog:
Cat. No.: HY-106698
CAS No.: 57475-17-9
Target:
Research Areas:
Brovincamine is an orally active slow Ca 2+ channel blocker and vasodilator. Brovincamine reduces Ca 2+ influx across the plasma membrane by blocking Ca 2+ channels. Brovincamine inhibits catecholamine secretion, cholinergic function, autonomic parasympathetic nervous system activity, cerebrovascular resistance, and nerve stimulation-induced convulsive responses. Brovincamine induces cerebrovascular, coronary, and intracranial vasodilation, improves cerebral cortical microcirculation, enhances cerebral metabolic activity, and increases capillary clearance efficiency. Brovincamine can be used in research related to cerebral ischemic diseases, cardiac ischemic diseases, and normal-tension glaucoma .
Cat. No.: HY-E70970
Target:
Research Areas:
Catechol-O-methyl Transferase, Porcine (EC 2.1.1.6) is one of several enzymes that degrade catecholamines such as dopamine, epinephrine, and norepinephrine.
Cat. No.: HY-17018
CAS No.: 148152-63-0
Synonyms: ABT 200 free acid; A-75200
Target:
Research Areas:
Napitane (A 75200) is a groundbreaking catecholamine uptake inhibitor that exhibits inhibitory effects on α-adrenergic receptors and shows promise for antidepressant activity in depression research.
Cat. No.: HY-105527
CAS No.: 79619-31-1
Target:
Research Areas:
Flavodilol is an orally active antihypertensive agent. Flavodilol extensively depletes catecholamines and serotonin in heart tissue of normotensive and spontaneously hypertensive rats (SHR). Flavodilol can be used for hypertension research .
Cat. No.: HY-W438378
CAS No.: 67423-45-4
Synonyms: HMPG piperazine
Category:
Target:
Cat. No.: HY-W683409
CAS No.: 119-48-2
Synonyms: 1064 Th
Target:
Research Areas:
Dimorpholamine (1064 Th) is a central nervous system stimulant. Dimorpholamine can increase the excitatory and inhibitory junction potentials at the neuromuscular junctions of crayfish. Dimorpholamine can also exert epinephrine-like pressor effects by promoting the release of catecholamines (mainly epinephrine) from the adrenal medulla. Dimorpholamine can be used in the research of respiratory failure as well as neurological and cardiovascular system diseases .
Cat. No.: HY-P1544A
Research Areas:
Cat. No.: HY-P702943
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: HSPA9; MOT; Prev. HSPA9B; Heat Shock 70kDa Protein 9B (Mortalin-2); 75 KDa Glucose-Regulated Protein; catecholamine-Regulated Protein 40; Stress-70 Protein, Mitochondrial; Heat Shock 70kD Protein 9B; GRP75; Mortalin, Perinuclear; PBP74; P66-Mortalin; Mths
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-N2332
CAS No.: 21019-30-7
Synonyms: MLA
Cat. No.: HY-100634
CAS No.: 14133-90-5
Synonyms: (±)-4-hydroxy Propranolol hydrochloride
Target:
Research Areas:
4-Hydroxypropranolol hydrochloride is a non-cardiac selective β-adrenergic receptor antagonist and a metabolite produced after oral administration of Propranolol (HY-B0573B). 4-Hydroxypropranolol hydrochloride also acts as a membrane stabilizer and possesses intrinsic sympathomimetic inhibitory activity. 4-Hydroxypropranolol hydrochloride blocks β-adrenergic receptors to antagonize the effects of catecholamines, acts as a partial β-adrenergic receptor agonist, and induces membrane stabilization. 4-Hydroxypropranolol hydrochloride alters heart rate, left ventricular contractility, and atrioventricular conduction time. 4-Hydroxypropranolol hydrochloride can be used in research related to cardiovascular and cerebrovascular diseases .
Cat. No.: HY-15746B
CAS No.: 101626-66-8
Target:
Research Areas:
Dobutamine tartrate is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine tartrate is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine tartrate can increase cardiac output and correct hypoperfusion .
Cat. No.: HY-14280R
CAS No.: 130929-57-6
Target:
Research Areas:
Entacapone (Standard) is the analytical standard of Entacapone. This product is intended for research and analytical applications. Entacapone is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC50s>50 µM). Entacapone can be used for the research of Parkinson's disease . Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders .
Cat. No.: HY-15746S
CAS No.: 1246815-74-6
Cat. No.: HY-15746S1
CAS No.: 1246818-96-1
Cat. No.: HY-15746R
CAS No.: 49745-95-1
Research Areas:
Dobutamine (hydrochloride) (Standard) is the analytical standard of Dobutamine (hydrochloride). This product is intended for research and analytical applications. Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion .
Cat. No.: HY-N2332AR
CAS No.: 351344-10-0
Synonyms: MLA citrate (Standard)
Research Areas:
Methyllycaconitine citrate (Standard) is the analytical standard of Methyllycaconitine citrate (HY-N2332A). This product is intended for research and analytical applications. Methyllycaconitine (MLA) citrate is a blood-brain barrier-permeable antagonist of α7 nicotinic acetylcholine receptor (α7nAChR) with an IC50 of 2 nM. Methyllycaconitine citrate inhibits Aβ25-35-induced autophagy by restoring the mTOR pathway, and prevents reactive oxygen species (ROS) production, microglial activation, reduced dopamine uptake, loss of dopaminergic terminals and catecholamine secretion. Methyllycaconitine citrate induces hippocampal glutamate efflux, enhances long-term potentiation, and improves memory acquisition. Methyllycaconitine citrate can be used in research related to Alzheimer's disease, cerebral palsy, ParKinson's disease and schizophrenia .
Cat. No.: HY-P702206
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ADRB2; ARB2; Prev. ADRB2R; Adrenergic, Beta-2-, Receptor, Surface; B2AR; Adrenoceptor Beta 2, Surface; Beta-2 Adrenergic Receptor; Adrenoceptor Beta 2 Surface; Beta-2 Adrenoreceptor; catecholamine Receptor; Beta-2 Adrenoceptor; ADRB2 Protein; ADRBR; BETA2AR; Adrenoceptor Beta 2; BAR
Species:
Human
Source:
E. coli Cell-free
Target:
Research Areas:
Bethanidine sulfate (BW 467C60) is an orally active antihypertensive agent and adrenergic neuron blocker. Bethanidine sulfate exerts its antihypertensive effect by inhibiting the release of norepinephrine from sympathetic nerve terminals. Bethanidine sulfate exhibits anti-ventricular arrhythmic activity. Bethanidine sulfate can be used in research related to hypertension, ventricular tachycardia, and ventricular fibrillation .
Cat. No.: HY-113416AS
Purity: 98.00%
Synonyms: DHEA sulfate-d6 sodium dihydrate; Prasterone sulfate-d6 sodium dihydrate
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
