114-85-2
Chemical Structure
Bethanidine sulfate
Synonym(s): BW 467C60
- CAS No.: 114-85-2
- Formula:C10H17N3O4S
- Molecular Weight:275.32
SMILES: O=S(O)(O)=O.CN/C(NC)=N/CC1=CC=CC=C1.[0.5]
Biological Activity: Bethanidine sulfate (BW 467C60) is an orally active antihypertensive agent and adrenergic neuron blocker. Bethanidine sulfate exerts its antihypertensive effect by inhibiting the release of norepinephrine from sympathetic nerve terminals. Bethanidine sulfate exhibits anti-ventricular arrhythmic activity. Bethanidine sulfate can be used in research related to hypertension, ventricular tachycardia, and ventricular fibrillation[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Bethanidine sulfate | Bethanidine sulfate (BW 467C60) is an orally active antihypertensive agent and adrenergic neuron blocker. Bethanidine sulfate exerts its antihypertensive effect by inhibiting the release of norepinephrine from sympathetic nerve terminals. Bethanidine sulfate exhibits anti-ventricular arrhythmic activity. Bethanidine sulfate can be used in research related to hypertension, ventricular tachycardia, and ventricular fibrillation. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. BOURA AL, et al. Adrenergic neurone blockade and other acute effects caused by N-benzyl-N'N"-dimethylguanidine and its ortho-chloro derivative. Br J Pharmacol Chemother. 1963;20(1):36-55. [Content Brief]
- [2]. Bacaner MB, et al. Antiarrhythmic, antifibrillatory, and hemodynamic actions of bethanidine sulfate: an orally effective analog of bretylium for suppression of ventricular tachyarrhythmias. Am J Cardiol. 1982;50(4):728-734. [Content Brief]
- [3]. Gifford RW. Bethanidine sulfate—a new antihypertensive agent. JAMa. 1965 Sep 13;193(11):901-5.
Keywords
