109 Results for "

solubilizing

" in MedChemExpress (MCE) Product Catalog:
Products (109)

109 Results for "solubilizing" in MCE Product Catalog:

Cat. No.: HY-164217
CAS No.: 2353529-47-0
Target:  

Drug Derivative

Research Areas:  

Others

β-D-Glucuronylmonomethylauristatin E is a derivative of MMAE (HY-15162). β-D-Glucuronylmonomethylauristatin E does not interact with pure phospholipid membranes, but can be effectively solubilized by micelles .
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Cat. No.: HY-158882
CAS No.: 2820046-26-0
Research Areas:  

Others

FLAC6 is a potent fluorinated detergent that can be used to solubilize membrane proteins (the native adenosine receptor A2AR, a G protein-coupled receptor, and two native transporters AcrB and BmrA). FLAC6 can maintain the structural and functional integrity of different membrane proteins .
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Cat. No.: HY-138193S
Synonyms: LMNG-d42
Lauryl maltose neopentyl glycol-d42 (LMNG-d42) is the deuterium labeled Lauryl maltose neopentyl glycol (HY-138193). Lauryl maltose neopentyl glycol (LMNG) is a detergent that can solubilize and stabilize membrane proteins. Lauryl maltose neopentyl glycol extracts integral membrane proteins from membranes, and improves substantially the stability of various membrane proteins, including G protein-coupled receptors and respiratory complexes .
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Cat. No.: HY-185061
CAS No.: 139361-84-5
Research Areas:  

Others

HEGA-10 is a mild detergent with a high critical micelle concentration (CMC), which can be used to dissolve and extract proteins (HIV-1 spike protein) from the membranes of virus-like particles (VLPs) .
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Cat. No.: HY-Y1173R
CAS No.: 1562-00-1
Synonyms: 2-Hydroxyethanesulfonic acid sodium (Standard); Sodium isethionate (Standard)
Isethionic acid sodium salt (Standard) (2-Hydroxyethanesulfonic acid sodium (Standard); Sodium isethionate (Standard)) is the analytical standard of Isethionic acid sodium salt (HY-Y1173). This product is intended for research and analytical applications. Isethionic acid sodium salt (Sodium 1-hydroxy-2-ethanesulfonate; Sodium 2-hydroxy-1-ethanesulfonate; Sodium 2-hydroxyethanesulfonate) is an endogenous mammalian Taurine (HY-B0351) metabolite. Isethionic acid sodium salt forms covalent ester linkages with cholic acid. It acts as a larval settlement inhibitor for Balanus amphitrite with larval toxicity. Isethionic acid sodium salt enables the low-temperature synthesis of highly hygroscopic water-soluble sulfonates, and its acylated derivatives serve as acidic wetting solubilizers. It is used in studies related to hepatic bile acid metabolism, biological control and organic synthesis .
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Cat. No.: HY-W250183C
CAS No.: 9005-00-9
Synonyms: Polyethylene glycol octadecyl ether (n=2)
Research Areas:  

Cancer

Polyoxyethylene (2) stearyl ether (Polyethylene glycol octadecyl ether (n=2)) is a nonionic surfactant. Polyoxyethylene (2) stearyl ether possesses the ability to emulsify, form vesicles, and reverse micelles. Polyoxyethylene (2) stearyl ether is commonly used in biological research such as gene delivery systems and nanovesicle preparation .
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Cat. No.: HY-W1113135
CAS No.: 2828447-14-7
Research Areas:  

Others

Carboxymethyl-β-cyclodextrin sodium salt is a negatively charged β-cyclodextrin derivative, as well as a metal ion chelator and solubilizing reagent. Carboxymethyl-β-cyclodextrin sodium salt forms stable aqueous complexes with Ba 2+, Ca 2+, Cd 2+, Ni 2+, Pb 2+, Sr 2+, and Zn 2+ ions. Carboxymethyl-β-cyclodextrin sodium salt derived hydrogel carriers support oral insulin delivery via paracellular permeation across Caco-2 monolayers and produce sustained hypoglycemic effects in diabetic mice. Carboxymethyl-β-cyclodextrin sodium salt can be conjugated onto folate-modified BSA nanoparticles to boost folate receptor-mediated endocytosis, elevate intracellular anticancer drug uptake and trigger cell apoptosis. Carboxymethyl-β-cyclodextrin sodium salt can be utilized for chiral separation in capillary electrophoresis, development of nanoscale drug carriers and nucleic acid transfection research .
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Cat. No.: HY-Y1890B
CAS No.: 61791-12-6
Cremophor EL-10 is a nonionic polyoxyethylene castor oil surfactant with multiple functions including organic solubilizer, mixed zinc anode corrosion inhibitor and dendrite growth inhibitor. By forming a physical barrier to block electrolyte contact and constructing oriented hydration channels to reduce the desolvation energy barrier of Zn 2+ , Cremophor EL-10 achieves a corrosion inhibition efficiency of over 99%. Cremophor EL-10 exerts no significant effects on the mitochondrial activity and cell viability of epithelial cells, making it suitable for in vitro drug delivery and biopharmaceutical research at concentrations ≤10% v/v. However, Cremophor EL-10 may induce sustained non-endothelium-dependent contraction in rat aortic rings and exert concentration-dependent inhibitory effects on acetylcholine-induced endothelium-dependent relaxation responses .
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Cat. No.: HY-W1113135A
CAS No.: 2828447-14-7
Research Areas:  

Others

Carboxymethyl-β-cyclodextrin sodium salt, for capillary electrophoresis is a negatively charged β-cyclodextrin derivative, as well as a metal ion chelator and solubilizing reagent. Carboxymethyl-β-cyclodextrin sodium salt, for capillary electrophoresis forms stable aqueous complexes with Ba 2+, Ca 2+, Cd 2+, Ni 2+, Pb 2+, Sr 2+, and Zn 2+ ions. Carboxymethyl-β-cyclodextrin sodium salt derived hydrogel carriers support oral insulin delivery via paracellular permeation across Caco-2 monolayers and produce sustained hypoglycemic effects in diabetic mice. Carboxymethyl-β-cyclodextrin sodium salt can be conjugated onto folate-modified BSA nanoparticles to boost folate receptor-mediated endocytosis, elevate intracellular anticancer drug uptake and trigger cell apoptosis. Carboxymethyl-β-cyclodextrin sodium salt can be utilized for chiral separation in capillary electrophoresis, development of nanoscale drug carriers and nucleic acid transfection research .
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