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Results for "

α-Pyrone

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Bacterial (1) Cholinesterase (ChE) (1) Drug Intermediate (2) Endogenous Metabolite (1) Fungal (4) Insecticide (1)
By Research Areas:	Cancer (1) Infection (5)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W013018

*α-Pyrone*	Drug Intermediate	Others
2-Pyrone is a drug intermediate, and its derivatives possess cytotoxicity .

HY-N15498

Gibepyrone D	Insecticide	Infection
Gibepyrone D is an α-pyrone compound found in Gibberella fujikuroi and the endophytic fungus Fusarium oxysporum 162. Gibepyrone D exhibits significant lethal activity against nematodes with an LC₅₀ value of 134 μg/mL (72 h) against the J2 larvae of Meloidogyne incognita. Gibepyrone D is promising for research of nematicides .

HY-165128

Alternapyrone	Fungal	Others
Alternapyrone is an α-pyrone compound found in fungi, some of which are phytotoxic to wheat seed germination, and its biosynthesis requires only three enzymes.

HY-N16412

Citreomontanin Citreomontanine	Drug Intermediate	Others
Citreomontanin (Citreomontanine) (Compound 3), an α‑Pyrone polyketide, is an intermediate of Citreoviripyrone A. Citreomontanin can be isolated from the mycelium of endophytic Penicillium sp. in Catharanthus roseus. Citreoviripyrone A has a moderate inhibitory activity on HCT116 cells growth .

HY-N18010

Opuntiol	Others	Others
Opuntiol is an α-pyrone found in the whole plant of Opuntia elatior .

HY-126610

Dactylfungin A	Fungal	Infection
Dactylfungin A, an α-pyrone-containing antifungal agent found in Dactylaria parvispora.

HY-N10273

Deoxyfusapyrone	Fungal	Infection
Deoxyfusapyrone is an antifungal alpha-pyrone from Fusarium semitectum. Deoxyfusapyrone shows a strong antibiotic activity towards Geotrichum candidum in disk diffusion assays, but is not toxic to Artemia salina larvae .

HY-N16447

Territrem C	Cholinesterase (ChE)	Others
Territrem C is an acetylcholinesterase (AchE) inhibitor with an IC₅₀ value of 0.23 μM. Territrem C, which belongs to α-pyrone meroterpenoids, can be isolated and produced from the fungus Penicillium sp. SK5GW1L .

HY-W017143

Antifungal agent 158	Fungal	Infection
Antifungal agent 158 is an α-pyrone derivative that can be found in Trichoderma harzianum, exhibiting antifungal activity against select plant-pathogenic fungi, including Chaetomium spp., Curvularia lunata, and Aspergillus flavus. Antifungal agent 158 is non-toxic to greenhouse-grown bean, corn, and tobacco plants. Antifungal agent 158 can be used for research on Aspergillus flavus infection .

HY-N19219

Wailupemycin F	Antibiotic Endogenous Metabolite Bacterial	Infection Cancer
Wailupemycin F is an Antibiotic and anticancer agent. Wailupemycin F is isolated from the marine-derived Streptomyces maritimus. Wailupemycin F exhibits antibacterial activity against Micrococcus luteus with a MIC of 1.1 μM. Wailupemycin F shows anticancer activity against myeloma. When used in combination with enterocin, Wailupemycin F exerts synergistic antibacterial activity against Micrococcus luteus, doubling its potency. Wailupemycin F can be used in studies related to Micrococcus luteus infection .

Gibepyrone D	Microorganisms Ketones, Aldehydes, Acids Source Classification	Insecticide
Gibepyrone D is an α-pyrone compound found in Gibberella fujikuroi and the endophytic fungus Fusarium oxysporum 162. Gibepyrone D exhibits significant lethal activity against nematodes with an LC₅₀ value of 134 μg/mL (72 h) against the J2 larvae of Meloidogyne incognita. Gibepyrone D is promising for research of nematicides .

Citreomontanin Citreomontanine	Microorganisms Ketones, Aldehydes, Acids Source Classification	Drug Intermediate
Citreomontanin (Citreomontanine) (Compound 3), an α‑Pyrone polyketide, is an intermediate of Citreoviripyrone A. Citreomontanin can be isolated from the mycelium of endophytic Penicillium sp. in Catharanthus roseus. Citreoviripyrone A has a moderate inhibitory activity on HCT116 cells growth .

Opuntiol	Opuntia elatior Mill. Structural Classification Natural Products Cactaceae Plants Source Classification	Others
Opuntiol is an α-pyrone found in the whole plant of Opuntia elatior .

Dactylfungin A	Microorganisms Antibiotics Other Antibiotics Source Classification	Fungal
Dactylfungin A, an α-pyrone-containing antifungal agent found in Dactylaria parvispora.

Deoxyfusapyrone	Infection Microorganisms Antifungal Classification of Application Fields Antibiotics Disease Research Disease Research Fields Other Antibiotics Source Classification	Fungal
Deoxyfusapyrone is an antifungal alpha-pyrone from Fusarium semitectum. Deoxyfusapyrone shows a strong antibiotic activity towards Geotrichum candidum in disk diffusion assays, but is not toxic to Artemia salina larvae .

Territrem C	Monophenols Microorganisms Phenols Source Classification	Cholinesterase (ChE)
Territrem C is an acetylcholinesterase (AchE) inhibitor with an IC₅₀ value of 0.23 μM. Territrem C, which belongs to α-pyrone meroterpenoids, can be isolated and produced from the fungus Penicillium sp. SK5GW1L .

Antifungal agent 158	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Fungal
Antifungal agent 158 is an α-pyrone derivative that can be found in Trichoderma harzianum, exhibiting antifungal activity against select plant-pathogenic fungi, including Chaetomium spp., Curvularia lunata, and Aspergillus flavus. Antifungal agent 158 is non-toxic to greenhouse-grown bean, corn, and tobacco plants. Antifungal agent 158 can be used for research on Aspergillus flavus infection .

Wailupemycin F	Structural Classification Monophenols Microorganisms Phenols Source Classification	Antibiotic Endogenous Metabolite Bacterial
Wailupemycin F is an Antibiotic and anticancer agent. Wailupemycin F is isolated from the marine-derived Streptomyces maritimus. Wailupemycin F exhibits antibacterial activity against Micrococcus luteus with a MIC of 1.1 μM. Wailupemycin F shows anticancer activity against myeloma. When used in combination with enterocin, Wailupemycin F exerts synergistic antibacterial activity against Micrococcus luteus, doubling its potency. Wailupemycin F can be used in studies related to Micrococcus luteus infection .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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α-Pyrone

Inhibitors & Agonists

NaturalProducts

Natural
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