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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
β-carboline derivative
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "β-carboline derivative" in MCE Product Catalog:
Cat. No.: HY-174156
CAS No.: 3092616-03-7
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Y2641, a etrahydro-β-carboline derivative, is an orally active dual RANKL/TNF-α inhibitor with Kd values of 3.984 μM and 18.59 μM for RANKL and TNF-α, respectively. Y2641 inhibits RANKL-induced osteoclastogenic and has anti-inflammatory and cartilage destruction. Y2641 can be used for study of osteoarthritis .
Cat. No.: HY-186203
CAS No.: 144434-73-1
8-Bromo-harmane is a β-carboline derivative with anti-HSV-1 activity. 8-Bromo-harmane is non-cytotoxic. 8-Bromo-harmane can be used for the research of herpes simplex virus 1 (HSV-1) infection .
Cat. No.: HY-179399
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β-carboline-ACS81 is a β-carboline derivative with potent antitumor properties. β-carboline-ACS81 induces apoptosis through the collapse of mitochondrial membrane potential and arrests cell cycle at G2/M phase in HL-60 cells. β-carboline-ACS81 possesses potent antiproliferative activity against HL-60 cells (IC50 = 1.52 μM). β-carboline-ACS81 can be used for the research of leukemia, histiocytic lymphoma, hepatocellular carcinoma, malignant melanoma, colorectal carcinoma and lung carcinoma .
Cat. No.: HY-182022
CAS No.: 3083425-49-1
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ZLWH-67 is a β-Carboline derivative and Antibacterial agent. ZLWH-67 inhibits DNA synthesis, suppresses biofilm formation, and increases reactive oxygen species (ROS) levels. ZLWH-67 exhibits potent in vitro antibacterial activity against MRSA (MIC = 0.5-4 μg/mL), S. epidermidis (MIC = 4 μg/mL), E. faecalis (MIC = 4-8 μg/mL), and S. pneumoniae (MIC = 16 μg/mL). ZLWH-67 displays anti-MRSA effects in murine skin and pneumonia infection models .
Cat. No.: HY-W269285
CAS No.: 72002-54-1
Synonyms: D-1,2,3,4-Tetrahydronorharman-3-carboxylic acid
Research Areas:
H-D-Tpi-OH (D-1,2,3,4-Tetrahydronorharman-3-carboxylic acid) is a tetrahydro-β-carboline derivative. H-D-Tpi-OH only slightly upregulates QR1, mildly inhibits the aromatase and NO synthesis pathways, and shows no significant in vitro anti-breast tumor proliferation activity. H-D-Tpi-OH can be used in cancer-related research .
