8-Bromo-harmane
8-Bromo-harmane is a β-carboline derivative with anti-HSV-1 activity. 8-Bromo-harmane is non-cytotoxic. 8-Bromo-harmane can be used for the research of herpes simplex virus 1 (HSV-1) infection.
For research use only. We do not sell to patients.
- CAS No.: 144434-73-1
- Formula: C12H9BrN2
- Molecular Weight:261.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
8-Bromo-harmane (5-10 μM; 21 h) exhibits partial antiviral activity against HSV-1 in Vero cells at non-cytotoxic concentrations, but does not prevent virus-induced cytopathic effects, with a CC50 greater than 120 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Vero cells infected with HSV-1
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Concentration:5; 10 μM
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Incubation Time:21 h
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Result:Had a cytotoxicity CC50 value greater than 120 μM.
Exhibited 62% antiviral activity against HSV-1 at 10 μM.
Exhibited 39% antiviral activity against HSV-1 at 5 μM.
Caused virus-driven cytopathic effects in treated cells.
Chemical Information
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CAS No. 144434-73-1
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Molecular Weight 261.12
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Formula C12H9BrN2
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SMILES
BrC1=CC=CC2=C1NC3=C2C=CN=C3C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
8-Bromo-harmane Related Classifications
HY-186203 Related Classifications
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