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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
β1-adrenoceptor
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "β1-adrenoceptor" in MCE Product Catalog:
21
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Endocrinology Cancer
Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a Ki of 697 nM at β1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris [1] .
17
17 Cited Publications
Cat. No.: HY-17503
CAS No.: 51384-51-1
Category:
Target:
17
17 Cited Publications
Cat. No.: HY-17503B
CAS No.: 56392-17-7
Target:
Research Areas:
Metoprolol tartrate is an orally active, selective β1-adrenoceptor antagonist. Metoprolol tartrate shows anti-inflammation, antitumor and anti-angiogenic properties [1] .
17
17 Cited Publications
Cat. No.: HY-17503A
CAS No.: 98418-47-4
Target:
Research Areas:
Metoprolol succinate is an orally active, selective β1-adrenoceptor antagonist. Metoprolol succinate shows anti-inflammation, antitumor and anti-angiogenic properties [1] .
2
2 Cited Publications
Target:
Research Areas:
L748337 is a potent β3-adrenergic receptor antagonist and displays selectivity over β1 and β2 receptors. The Ki values of L748337 for β3-, β2- and β1-adrenoceptors are 4.0 nM, 204 nM and 390 nM, respectively [1]. L748337 couples predominantly to Gi to activate MAPK signaling and increases phosphorylation of Erk1/2 with pEC50 value of 11.6 . L748337 can be used for the research of cancer, nonalcoholic fatty liver disease (NAFLD), and cardiovascular related diseases [1] .
2
2 Cited Publications
Target:
Research Areas:
Ro 363 hydrochloride, an effective inotropic stimulant, is a potent and highly selective β1-adrenoceptor agonist. Ro 363 hydrochloride is a cardiovascular modulator that reduces diastolic blood pressure and pronounces increases in myocardial contractility [1] .
Target:
Research Areas:
Carmoterol hydrochloride is a highly potent, selective and long-acting β2-adrenoceptor agonist with the pEC50 of 10.19. Carmoterol has 53 times higher affinity for the β2-adrenoceptors than for the β1-adrenoceptors. Carmoterol hydrochloride can be used for the research of asthma and chronic obstructive pulmonary disease (COPD) [1] .
Synonyms: Corwin hemifumarate; ICI 118587 hemifumarate
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease
Xamoterol (Corwin; ICI 118587) hemifumarate is an orally active and selective β1-adrenoceptor partial agonist. Xamoterol hemifumarate acts as agonist at low sympathetic tone, antagonist at high sympathetic tone, with context-dependent cardiovascular effects including modulated heart rate, blood pressure, and cardiac output. Xamoterol hemifumarate can be used for the research of heart failure, postural hypotension, and ischemic heart disease [1] .
Synonyms: CGP 20712 mesylate
Target:
Research Areas:
CGP 20712 A (CGP 20712 mesylate) is a highly selective β1-adrenoceptor antagonist with an IC50 of 0.7 nM. CGP 20712 A exhibits ~10,000-fold selectivity over β2-adrenoceptors [1].
Cat. No.: HY-17503AS
CAS No.: 1219798-61-4
Cat. No.: HY-17498S
CAS No.: 1202864-50-3
Synonyms: (RS)-Atenolol-d7
Cat. No.: HY-17503R
CAS No.: 51384-51-1
Research Areas:
Metoprolol (Standard) is the analytical standard of Metoprolol. This product is intended for research and analytical applications. Metoprolol is an orally active, selective β1-adrenoceptor antagonist. Metoprolol shows anti-inflammation, antitumor and anti-angiogenic properties [1] .
Cat. No.: HY-17503AR
CAS No.: 98418-47-4
Research Areas:
Metoprolol (succinate) (Standard) is the analytical standard of Metoprolol (succinate). This product is intended for research and analytical applications. Metoprolol succinate is an orally active, selective β1-adrenoceptor antagonist. Metoprolol succinate shows anti-inflammation, antitumor and anti-angiogenic properties [1] .
Cat. No.: HY-17498R
CAS No.: 29122-68-7
Synonyms: (RS)-Atenolol (Standard)
Research Areas:
Atenolol (Standard) is the analytical standard of Atenolol. This product is intended for research and analytical applications. Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a Ki of 697 nM atβ1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris [1] .
Target:
Research Areas:
CGP 20712 dihydrochloride is a highly selective β1-adrenoceptor antagonist with an IC50 of 0.7 nM. CGP 20712 dihydrochloride exhibits ~10,000-fold selectivity over β2-adrenoceptors [1].
Cat. No.: HY-123268
CAS No.: 74513-77-2
Target:
Research Areas:
Ro 363, an effective inotropic stimulant, is a potent and highly selective β1-adrenoceptor agonist. RO 363 is a cardiovascular modulator that reduces diastolic blood pressure and pronounces increases in myocardial contractility [1] .
Cat. No.: HY-17503S3
CAS No.: 959786-79-9
Cat. No.: HY-101327
CAS No.: 81801-12-9
Synonyms: Corwin; ICI 118587
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease
Xamoterol (Corwin; ICI 118587) is an orally active and selective β1-adrenoceptor partial agonist. Xamoterol acts as agonist at low sympathetic tone, antagonist at high sympathetic tone, with context-dependent cardiovascular effects including modulated heart rate, blood pressure, and cardiac output. Xamoterol can be used for the research of heart failure, postural hypotension, and ischemic heart disease [1] .
Cat. No.: HY-17503BR
CAS No.: 56392-17-7
Research Areas:
Metoprolol (tartrate) (Standard) is the analytical standard of Metoprolol (tartrate). This product is intended for research and analytical applications. Metoprolol tartrate is an orally active, selective β1-adrenoceptor antagonist. Metoprolol tartrate shows anti-inflammation, antitumor and anti-angiogenic properties [1] .
Cat. No.: HY-17503D
CAS No.: 56392-18-8
Target:
Research Areas:
Metoprolol Hydrochloride is an orally active and selective β1-adrenoceptor antagonist. Metoprolol Hydrochloride exhibits anti-inflammatory, antitumor, and anti-angiogenic properties [1] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
