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13 Results for "
1,3,4-Oxadiazole
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "1,3,4-Oxadiazole" in MCE Product Catalog:
Cat. No.: HY-W131122
CAS No.: 288-99-3
1,3,4-Oxadiazoles are a class of synthetic compounds with important medicinal value, which show a variety of biological activities such as anticonvulsant, antidepressant, analgesic, anti-inflammatory, antiallergic, antipsychotic, antimicrobial, antituberculous, antitumor, and antiviral. 1,3,4-Oxadiazole derivatives need to be further developed .
Cat. No.: HY-W015224
CAS No.: 1912-33-0
Category:
Natural Products Marine natural products Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-161305
CAS No.: 2243575-79-1
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Research Areas:
SE-7552, a 2-(difluoromethyl)-1,3,4-oxadiazole (DFMO) derivative, is an orally active, highly selective, non-hydroxamate HDAC6 inhibitor with an IC50 of 33 nM. SE-7552 is greater than 850-fold selectivity versus all other known HDAC isozymes. SE-7552 is capable of blocking multiple myeloma growth in vivo. SE-7552 acts as an anti-obesity agent in diet-induced obese mice .
Cat. No.: HY-W104752
CAS No.: 15264-63-8
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Research Areas:
Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol (Compound 3n) is an antimicrobial and antioxidant agent, that inhibits Escherichia coli and Staphylococcus epidermidis, with MIC of 8 and 4 μg/mL. 5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol exhibits antioxidant activity with IC50 of 17.47 μM using DPPH free radical-scavenging method .
Cat. No.: HY-141555
CAS No.: 333409-31-7
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5,5′-(1,3-Propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione is a weak inhibitor for snake venom and human recombinant phosphodiesterase 1 with IC50 of 429 and 467 μM. 5,5′-(1,3-Propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione inhibits mushroom tyrosinase weakly, with Ki of 1.9 μM .
Cat. No.: HY-161306
CAS No.: 2760854-72-4
ITF5924 (compound 1) is a potent and highly selective HDAC6 inhibitor with an IC50 of 7.7 nM. ITF5924 shows greater than 104-fold selectivity for HDAC6 over all other HDAC subtypes. ITF5924 containing a difluoromethyl-1,3,4-oxadiazole (DFMO) moiety is slow-binding substrate analog of HDAC6 that undergo an enzyme-catalyzed ring opening reaction, forming a tight and long-lived enzyme-inhibitor complex .
Cat. No.: HY-172102
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NLRP3-IN-68 (Compound 2d) is a 1,3,4-oxadiazole derivative. NLRP3-IN-68 has strong anti-inflammatory and antioxidant activities, which can inhibit inflammatory cytokines secretion, iNOS expression and NLRP3 inflammasome activation. NLRP3-IN-68 can be used in the research of anti-inflammatory drugs .
Cat. No.: HY-W104812
CAS No.: 10600-83-6
Synonyms: 2,5-Bis(4-hydroxyphenyl)-1,3,4-Oxadiazole
4,4'-(1,3,4-Oxadiazole-2,5-diyl)diphenol (2,5-Bis(4-hydroxyphenyl)-1,3,4-oxadiazole) is a metal-organic framework (MOF).
Cat. No.: HY-W1049941
CAS No.: 2787530-35-0
5,5'-(1,3,4-Oxadiazole-2,5-diyl)diisophthalic acid is a metal-organic framework (MOF).
Cat. No.: HY-W586830
CAS No.: 41259-89-6
4,4′-(1,3,4-Oxadiazole-2,5-diyl)bis[benzoic acid] is a metal-organic framework (MOF).
Cat. No.: HY-W075197
CAS No.: 15420-02-7
Synonyms: 2,5-Bis(4-pyridyl)-1,3,4-Oxadiazole
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
