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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
11β-hydroxylase
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "11β-hydroxylase" in MCE Product Catalog:
17
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Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
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4
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Osilodrostat (LCI699) is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM. Osilodrostat is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat inhibits aldosterone and corticosterone synthesis. Osilodrostat has blood pressure lowering ability. Osilodrostat can be used for research of Cushing syndrome (CS) .
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Osilodrostat (LCI699) phosphate is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM. Osilodrostat phosphate is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat phosphate inhibits aldosterone and corticosterone synthesis. Osilodrostat phosphate has blood pressure lowering ability. Osilodrostat phosphate can be used for research of Cushing syndrome (CS) .
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1 Cited Publications
Synonyms: 4-Androsten-11β-ol-3,17-dione
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1 Cited Publications
Category:
Natural Products Animals Marine natural products Other marine organisms Disease Research Fields Cancer
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1
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Category:
Infection Other Diseases Disease markers Endogenous metabolite Disease Research Fields Cancer Steroids
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Synonyms: 4-Androsten-11β-ol-3,17-dione-d7
Cat. No.: HY-P10447
CAS No.: 103651-09-8
Synonyms: Fengycin IX; SNA-60-367-3
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Cat. No.: HY-P4755
CAS No.: 282726-24-3
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Cat. No.: HY-E71386
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1-Deoxypentalenic acid 11β-hydroxylase (EC 1.14.11.35) requires Fe(II) and ascorbate.
Cat. No.: HY-P3100
CAS No.: 939960-34-6
Cat. No.: HY-125357
CAS No.: 148619-41-4
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Cat. No.: HY-114464S
CAS No.: 2687960-98-9
Synonyms: 4-Androsten-11β-ol-3,17-dione-d4
Category:
Alkaloids Neurological Disease Pyridine Alkaloids Endogenous metabolite Disease Research Fields Endocrinology
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Cat. No.: HY-158104
Cat. No.: HY-113405R
CAS No.: 641-77-0
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
