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Results for "

2-aminopyrimidine compound

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

2

Biochemical Assay Reagents

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-41340

    Biochemical Assay Reagents Drug Intermediate Others
    2-Aminopyrimidine is an important heterocyclic intermediate. 2-Aminopyrimidine can undergo various reactions such as alkylation and acylation, and can be used for the synthesis of other active compounds .
    2-Aminopyrimidine
  • HY-41340R

    Biochemical Assay Reagents Reference Standards Drug Intermediate Others
    2-Aminopyrimidine (Standard) is the analytical standard of 2-Aminopyrimidine (HY-41340). This product is intended for research and analytical applications. 2-Aminopyrimidine is an important heterocyclic intermediate. 2-Aminopyrimidine can undergo various reactions such as alkylation and acylation, and can be used for the synthesis of other active compounds.
    2-Aminopyrimidine (Standard)
  • HY-W720946

    Isotope-Labeled Compounds Biochemical Assay Reagents Others
    2-Aminopyrimidine-d2 is the deuterium labeled 2-Aminopyrimidine (HY-41340). 2-Aminopyrimidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    2-Aminopyrimidine-d2
  • HY-162530

    CDK Cancer
    CDK4/6-IN-20 (Compound II-5) is a CDK4/CDK6 inhibitor with IC50 values ​​of 1.9, 14.2 nM, respectively. CDK4/6-IN-20 also inhibits cell proliferation and can be used in cancer research .
    CDK4/6-IN-20
  • HY-149889

    Apoptosis EGFR Cancer
    EGFR-IN-78 (compound A5),a 2-aminopyrimidine derivative,is a reversible inhibitor of EGFR C797S-TK,and also an inducer of apoptosis. EGFR-IN-78 shows anti-proliferative activity,inhibits EGFR phosphorylation and arrests cell cycle at G2/M phase .
    EGFR-IN-78
  • HY-162529

    CDK Cancer
    CDK4/6-IN-19 (Compound II-7) is a CDK4/CDK6 inhibitor with IC50 values ​​of 0.2, 5.0 nM, respectively. CDK4/6-IN-19 also inhibits cell proliferation and can be used in cancer research .
    CDK4/6-IN-19
  • HY-123599

    DNA/RNA Synthesis Cancer
    IACS-4619 (compound 4) is a highly selective 2-aminopyrimidine-based MTH1 (MutT homolog 1) inhibitor (IC50=0.2 nM). IACS-4619 inhibits MTH1 by blocking its hydrolysis of oxidized purine nucleotides such as 8-oxo-dGTP, thereby preventing MTH1 from inhibiting the incorporation of oxidized nucleotides into DNA. IACS-4619 significantly inhibits endogenous MTH1 activity in MTH1-overexpressing U2OS cells, but without antiproliferative or cytotoxic effects on various human cancer and normal cell lines. IACS-4619 can be used in oncology research related to the MTH1 target .
    IACS-4619

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