CDK4/6-IN-19
CDK4/6-IN-19 (Compound II-7) is a CDK4/CDK6 inhibitor with IC50 values of 0.2, 5.0 nM, respectively. CDK4/6-IN-19 also inhibits cell proliferation and can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 3033950-86-3
- Formula: C23H27ClFN5O3S
- Molecular Weight:508.01
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CDK4 0.2 nM (IC50) |
CDK6 5.0 nM (IC50) |
CDK4/6-IN-19 inhibits the proliferation of MCF7 and T47D cells with IC50 values of 217 and 212 nM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3033950-86-3
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Molecular Weight 508.01
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Formula C23H27ClFN5O3S
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SMILES
O=S(N1C[C@@H](O)[C@H](NC2=NC=C(Cl)C(C3=CC(C4(CCCC4)C(C)=N5)=C5C(F)=C3)=N2)CC1)(C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK4/6-IN-19 Related Classifications
HY-162529 Related Classifications
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