CDK4/6-IN-20
CDK4/6-IN-20 (Compound II-5) is a CDK4/CDK6 inhibitor with IC50 values of 1.9, 14.2 nM, respectively. CDK4/6-IN-20 also inhibits cell proliferation and can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 3033950-84-1
- Formula: C23H24FN5O2
- Molecular Weight:421.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CDK4 1.9 nM (IC50) |
CDK6 14.2 nM (IC50) |
CDK4/6-IN-20 inhibits the proliferation of MCF7 and T47D cells with IC50 values of 169 and 92 nM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3033950-84-1
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Molecular Weight 421.47
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Formula C23H24FN5O2
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SMILES
O[C@@H]1COCC[C@H]1NC2=NC=C(C#N)C(C3=CC(C4(CCCC4)C(C)=N5)=C5C(F)=C3)=N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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