21 Results for "

4-Cholesten-3-one

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "4-Cholesten-3-one" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P2848
CAS No.: 9028-76-6
Synonyms: ChOx, Microorganism
Target:  

Xanthine Oxidase

Research Areas:  

Infection Metabolic Disease

Cholesterol oxidase, Microorganism (ChOx, Microorganism) (EC 1.1.3.6) is a cholesterol oxidase identified from bacterial sources. Cholesterol oxidase, Microorganism catalyzes the oxidation of cholesterol to 4-cholesten-3-one, while simultaneously reducing oxygen to hydrogen peroxide. Cholesterol oxidase, Microorganism retains its enzymatic activity and exhibits improved catalytic efficiency upon immobilization. Cholesterol oxidase, Microorganism is applicable for cholesterol detection, steroid biotransformation, and research on tuberculosis-related diseases .
loading...
    loading...
Cat. No.: HY-113365
CAS No.: 601-57-0
Purity:  99.81%
Synonyms: 4-Cholesten-3-one
Cholestenone (4-cholesten-3-one) is an orally available antimicrobial agent that is metabolized primarily in the liver as an intermediate oxidation product of cholesterol. Cholestenone inhibits human dermal fibroblast migration and fights Helicobacter pylori infection in vitro and in mouse models by inhibiting cholesterol-α-D-glucopyranoside (CGL). Cholestenone also alleviates metabolic disorders caused by obesity in db/db mice .
loading...
    loading...
Cat. No.: HY-113259
CAS No.: 3862-25-7
Purity:  99.60%
7α-Hydroxy-4-cholesten-3-one is an intermediate in synthesis of bile acids from cholesterol. 7α-Hydroxy-4-cholesten-3-one is a pregnane X receptor (PXR) agonist. 7α-Hydroxy-cholest-4-en-3-one is a biomarker for bile acid loss, irritable bowel syndrome, and other diseases associated with defective bile acid biosynthesis. 7α-Hydroxy-cholest-4-en-3-one is the physiological substrate for CYP8B1 .
loading...
    loading...
Cat. No.: HY-113365S
CAS No.: 72560-60-2
Purity:  ≥99.0%
Synonyms: 4-Cholesten-3-one-d5
Cholestenone-d5 is the deuterium labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells .
loading...
    loading...
Cat. No.: HY-113259S
CAS No.: 2260669-17-6
Purity:  ≥98.0%
7α-Hydroxy-4-cholesten-3-one-d7 is the deuterium labeled 7α-Hydroxy-4-cholesten-3-one. 7α-Hydroxy-4-cholesten-3-one is an intermediate in synthesis of bile acids from cholesterol. 7α-Hydroxy-4-cholesten-3-one is a pregnane X receptor (PXR) agonist. 7α-Hydroxy-cholest-4-en-3-one is a biomarker for bile acid loss, irritable bowel syndrome, and other diseases associated with defective bile acid biosynthesis. 7α-Hydroxy-cholest-4-en-3-one is the physiological substrate for CYP8B1 .
loading...
    loading...
Cat. No.: HY-113365S2
CAS No.: 82938-09-8
Synonyms: 4-Cholesten-3-one-13C2
Cholestenone- 13C2 is the 13C labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells .
loading...
    loading...
Cat. No.: HY-113365R
CAS No.: 601-57-0
Synonyms: 4-Cholesten-3-one (Standard)
Clebopride (malate) (Standard) is the analytical standard of Clebopride (malate). This product is intended for research and analytical applications. Clebopride malate is a dopamine antagonist used in the study of functional gastrointestinal disorders.
loading...
    loading...
Cat. No.: HY-W414548
CAS No.: 4725-24-0
7α,27-Dihydroxycholesterol is an oxysterol, a human metabolite, and a ligand for EBI2 (GPR183), which is involved in lipid synthesis. 7α,27-Dihydroxycholesterol mediates the chemotaxis of cells expressing EBI2. 7α,27-Dihydroxycholesterol can be converted into 7α,27-dihydroxy-4-cholesten-3-one (HY-W414457), thereby inhibiting HMG-CoA reductase (HMGCR), the rate-limiting enzyme in cholesterol synthesis .
loading...
    loading...
Cat. No.: HY-113365S1
CAS No.: 68165-57-1
Purity:  ≥99.0%
Synonyms: 4-Cholesten-3-one-13C
Cholestenone- 13C is the 13C labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells .
loading...
    loading...
Cat. No.: HY-P2848A
CAS No.: 9028-76-6
Synonyms: ChOx, rhodococcus sp
Target:  

Xanthine Oxidase

Research Areas:  

Infection Metabolic Disease

Cholesterol oxidase, rhodococcus sp (ChOx, rhodococcus sp) (EC 1.1.3.6) is a cholesterol oxidase identified from bacterial sources. Cholesterol oxidase, rhodococcus sp catalyzes the oxidation of cholesterol to 4-cholesten-3-one, while simultaneously reducing oxygen to hydrogen peroxide. Cholesterol oxidase, rhodococcus sp retains its enzymatic activity and exhibits improved catalytic efficiency upon immobilization. Cholesterol oxidase, rhodococcus sp is applicable for cholesterol detection, steroid biotransformation, and research on tuberculosis-related diseases .
loading...
    loading...
Cat. No.: HY-113259R
CAS No.: 3862-25-7
7α-Hydroxy-4-cholesten-3-one (Standard) is the analytical standard of 7α-Hydroxy-4-cholesten-3-one. This product is intended for research and analytical applications. 7α-Hydroxy-4-cholesten-3-one is an intermediate in synthesis of bile acids from cholesterol. 7α-Hydroxy-4-cholesten-3-one is a pregnane X receptor (PXR) agonist. 7α-Hydroxy-cholest-4-en-3-one is a biomarker for bile acid loss, irritable bowel syndrome, and other diseases associated with defective bile acid biosynthesis. 7α-Hydroxy-cholest-4-en-3-one is the physiological substrate for CYP8B1 .
loading...
    loading...
Cat. No.: HY-113365S3
CAS No.: 2389048-48-8
Synonyms: 4-Cholesten-3-one-d7
Cholestenone-d7 is deuterium labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop
loading...
    loading...
Cat. No.: HY-180601
CAS No.: 98774-41-5
7α,25-Dihydroxy-4-cholesten-3-one is a sterol metabolite. 25-Hydroxycholesterol is 7α-hydroxylated and further oxidized to 7α,25-Dihydroxy-4-cholesten-3-one .
loading...
    loading...
Cat. No.: HY-W414457
CAS No.: 192187-67-0
Target:  

Others

Research Areas:  

Metabolic Disease

7α,27-Dihydroxy-4-cholesten-3-one is an oxysterol.
loading...
    loading...
Cat. No.: HY-113259AS
CAS No.: 1262046-74-1
7β-Hydroxy-4-cholesten-3-one-d7 is the deuterium labeled 7β-Hydroxy-4-cholesten-3-one .
loading...
    loading...
Cat. No.: HY-P2848B
Synonyms: ChOx, Streptomyces sp.
Target:  

Xanthine Oxidase

Research Areas:  

Metabolic Disease

Cholesterol oxidase, Streptomyces sp. (ChOx, Streptomyces sp.) (EC 1.1.3.6) is a cholesterol oxidase identified from bacterial sources. Cholesterol oxidase, Streptomyces sp. catalyzes the oxidation of cholesterol to 4-cholesten-3-one, while simultaneously reducing oxygen to hydrogen peroxide. Cholesterol oxidase, Streptomyces sp. retains its enzymatic activity and exhibits improved catalytic efficiency upon immobilization. Cholesterol oxidase, Streptomyces sp. is applicable for cholesterol detection, steroid biotransformation, and research on tuberculosis-related diseases .
loading...
    loading...
Cat. No.: HY-P2848C
Synonyms: ChOx, Pseudomonas sp.
Target:  

Xanthine Oxidase

Research Areas:  

Metabolic Disease

Cholesterol oxidase, Pseudomonas sp. (ChOx, Pseudomonas sp.) (EC 1.1.3.6) is a cholesterol oxidase identified from bacterial sources. Cholesterol oxidase, Pseudomonas sp. catalyzes the oxidation of cholesterol to 4-cholesten-3-one, while simultaneously reducing oxygen to hydrogen peroxide. Cholesterol oxidase, Pseudomonas sp. retains its enzymatic activity and exhibits improved catalytic efficiency upon immobilization. Cholesterol oxidase, Pseudomonas sp. is applicable for cholesterol detection, steroid biotransformation, and research on tuberculosis-related diseases .
loading...
    loading...
Cat. No.: HY-P2848D
Synonyms: ChOx, Nocardia sp.
Target:  

Xanthine Oxidase

Research Areas:  

Metabolic Disease

Cholesterol oxidase, Nocardia sp. (ChOx, Nocardia sp.) (EC 1.1.3.6) is a cholesterol oxidase identified from bacterial sources. Cholesterol oxidase, Nocardia sp. catalyzes the oxidation of cholesterol to 4-cholesten-3-one, while simultaneously reducing oxygen to hydrogen peroxide. Cholesterol oxidase, Nocardia sp. retains its enzymatic activity and exhibits improved catalytic efficiency upon immobilization. Cholesterol oxidase, Nocardia sp. is applicable for cholesterol detection, steroid biotransformation, and research on tuberculosis-related diseases .
loading...
    loading...
Cat. No.: HY-P2848E
Synonyms: ChOx, PEG Modified
Target:  

Xanthine Oxidase

Research Areas:  

Metabolic Disease

Cholesterol oxidase, PEG Modified (ChOx, PEG Modified) (EC 1.1.3.6) is a cholesterol oxidase identified from bacterial sources. Cholesterol oxidase, PEG Modified catalyzes the oxidation of cholesterol to 4-cholesten-3-one, while simultaneously reducing oxygen to hydrogen peroxide. Cholesterol oxidase, PEG Modified retains its enzymatic activity and exhibits improved catalytic efficiency upon immobilization. Cholesterol oxidase, PEG Modified is applicable for cholesterol detection, steroid biotransformation, and research on tuberculosis-related diseases .
loading...
    loading...
Cat. No.: HY-P810864
Synonyms: CYP12, CYP8B1, 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, 7-alpha-hydroxy-4-Cholesten-3-one 12-alpha-hydroxylase, CYPVIIIB1, Cytochrome P450 8B1, Sterol 12-alpha-hydroxylase

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

loading...
    loading...