6 Results for "

Aβ42-IN-2

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Aβ42-IN-2" in MCE Product Catalog:

Cat. No.: HY-136866
CAS No.: 1914989-80-2
Purity:  98.00%
Target:  

γ-secretase

Research Areas:  

Neurological Disease

Aβ42-IN-2 (compound example 36) is a γ-secretase modulator. Aβ42-IN-2 has an IC50 of 6.5 nM for Αβ42. Aβ42-IN-2 can be used for the research of Alzheimer's disease .
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24
24 Cited Publications
Cat. No.: HY-B0034
CAS No.: 120011-70-3
Synonyms: E2020
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease Cancer

Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM for AChE activity. Donepezil shows high selectivity for AChE over BuChE . Donepezil exhibits neuroprotective effect on Aβ42 neurotoxicity .
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Cat. No.: HY-B0034S
CAS No.: 1883548-90-0
Synonyms: E2020-d5
Donepezil-d5 (hydrochloride) is deuterium labeled Donepezil (Hydrochloride). Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM for AChE activity. Donepezil shows high selectivity for AChE over BuChE . Donepezil exhibits neuroprotective effect on Aβ42 neurotoxicity .
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Cat. No.: HY-149764
CAS No.: 6314-40-5
Purity:  99.92%
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Aβ42 agonist-2 (compound 7b) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-2 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-2 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells .
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Cat. No.: HY-B0034S1
CAS No.: 1219798-88-5
Synonyms: E2020-d4
Donepezil-d4 (hydrochloride) is the deuterium labeled Donepezil hydrochloride. Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM for AChE activity. Donepezil shows high selectivity for AChE over BuChE . Donepezil exhibits neuroprotective effect on Aβ42 neurotoxicity .
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Cat. No.: HY-B0034R
CAS No.: 120011-70-3
Synonyms: E2020 (Standard)
Donepezil (Hydrochloride) (Standard) is the analytical standard of Donepezil (Hydrochloride). This product is intended for research and analytical applications. Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM for AChE activity. Donepezil shows high selectivity for AChE over BuChE . Donepezil exhibits neuroprotective effect on Aβ42 neurotoxicity .
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