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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
48 Results for "
A2a/A2b adenosine receptor
" in MedChemExpress (MCE) Product Catalog:
Products (48)
48 Results for "A2a/A2b adenosine receptor" in MCE Product Catalog:
18
18 Publications Verification
Synonyms: Adenine riboside; D-adenosine
18
18 Publications Verification
Cat. No.: HY-19533
CAS No.: 160098-96-4
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SCH 58261 is a potent, selective and competitive antagonist of adenosine A2A receptor with an IC50 of 15 nM, and displays 323-, 53- and 100-fold more selective for A2A receptor than A1, A2B, and A3 receptors, respectively .
7
7 Cited Publications
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BAY 60-6583 is a potent and high-affinity agonist of adenosine A2B receptor (EC50=3 nM) over A1, A2A, and A3 receptors. BAY 60-6583 binds to mouse, rabbit, and dog A2BAR with Ki values of 750 nM, 340 nM and 330 nM, respectively. BAY 60-6583 has a cardioprotective effect in a myocardial ischemia model .
3
3 Cited Publications
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PSB-603 is a potent and highly selective A2B adenosine receptor antagonist exhibiting a Ki value of 0.553 nM and virtually no affinity for the human and rat A1 and A2A and the human A3 receptors up to a concentration of 10 μM .
1
1 Cited Publications
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Research Areas:
CGS 15943 is an orally bioavailable non-xanthine Adenosine Receptor antagonist. Its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM in transfected CHO cells, respectively. .
1
1 Cited Publications
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Research Areas:
MRS-1706 is a potent and selective adenosine A2B receptor inverse agonist. MRS-1706 has Ki values of 1.39, 112, 157, and 230 nM for human A2B, A2A, A1 and A3 receptors respectively. MRS-1706 blocks adenosine-mediated cAMP induction .
1
1 Cited Publications
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Research Areas:
M1069 is a selective and orall active, dual A2A/A2B adenosine receptor antagonist with a selectivity of >100 fold against the A1 and A3 receptors. M1069 counteracts immune-suppressive mechanisms of adenosine, and exhibits anti-tumor activity .
1
1 Cited Publications
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Research Areas:
M1069 (free base) is a selective and orall active, dual A2A/A2B adenosine receptor antagonist with a selectivity of >100 fold against the A1 and A3 receptors. M1069 (free base) counteracts immune-suppressive mechanisms of adenosine, and exhibits anti-tumor activity .
Cat. No.: HY-B0228S1
CAS No.: 159496-13-6
Synonyms: Adenine riboside-13C5; D-adenosine-13C5
Cat. No.: HY-B0228S11
CAS No.: 168566-57-2
Synonyms: Adenine riboside-15N5; D-adenosine-15N5
Cat. No.: HY-B0228S13
CAS No.: 1887761-94-5
Synonyms: Adenine riboside-13C10; D-adenosine-13C10
Cat. No.: HY-B0228S9
CAS No.: 202406-75-5
Cat. No.: HY-B0228S6
CAS No.: 82741-17-1
Synonyms: Adenine riboside-d2; D-adenosine-d2
Cat. No.: HY-B0228S4
CAS No.: 201996-55-6
Synonyms: Adenine riboside-1′-13C; D-adenosine-1′-13C
Cat. No.: HY-B0228S
CAS No.: 109923-50-4
Synonyms: Adenine riboside-d1; D-adenosine-d
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BAY-545 is a potent and selective A2B adenosine receptor antagonist, with an IC50 of 59 nM. BAY-545 also exhibits IC50s of 66, 400, 280 nM for human, mouse, rat A2B adenosine receptor in cells, respectively, and a Ki of 97 nM for human A2B adenosine receptor, with more selectivity over A1, A2A, and A3 adenosine receptor .
Cat. No.: HY-B0228S5
CAS No.: 54447-57-3
Synonyms: Adenine riboside-13C; D-adenosine-13C
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Research Areas:
LUF5834 is a selective A2B adenosine receptor (A2BR) partial agonist (EC50 = 12 nM). LUF5834 is also a partial A1/A2A adenosine receptor agonist (lacking selectivity) with Ki values of 2.6 and 28 nM, respectively .
Cat. No.: HY-B0228S12
Synonyms: Adenine riboside-d13; D-adenosine-d13
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
