104615-18-1
104615-18-1
Chemical Structure
CGS 15943
- CAS No.: 104615-18-1
- Formula:C13H8ClN5O
- Molecular Weight:285.69
IUPAC Name: 9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine
InChIKey: MSJODEOZODDVGW-UHFFFAOYSA-N
SMILES: NC1=NC2=C(C=C(Cl)C=C2)C3=NC(C4=CC=CO4)=NN13
Biological Activity: CGS 15943 is an orally bioavailable non-xanthine Adenosine Receptor antagonist. Its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM in transfected CHO cells, respectively. [1][2].
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CGS 15943 | 99.55% | CGS 15943 is an orally bioavailable non-xanthine Adenosine Receptor antagonist. Its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM in transfected CHO cells, respectively. . | ||||||||||||||||||||
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CGS 15943 (Standard) | ≥98% | CGS 15943 (Standard) is the analytical standard of CGS 15943. This product is intended for research and analytical applications. CGS 15943 is an orally bioavailable non-xanthine Adenosine Receptor antagonist. Its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM in transfected CHO cells, respectively. . | ||||||||||||||||||||
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References
- [1]. Gao Y, et al. CGS 15943, an adenosine A2 receptor antagonist, reduces cerebral ischemic injury in the Mongolian gerbil. Life Sci. 1994;55(3):PL61-5. [Content Brief]
- [2]. Klotz KN, et al. Adenosine receptors and their ligands. Naunyn Schmiedebergs Arch Pharmacol. 2000 Nov;362(4-5):382-91. [Content Brief]
Keywords
