21 Results for "

Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2" in MCE Product Catalog:

Cat. No.: HY-P10215
Target:  

Parasite

Research Areas:  

Infection

Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent Plasmodium subtilisin-like protease 1 (SUB1) inhibitor. SUB1-IN-1 shows IC50 values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .
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1 Cited Publications
Cat. No.: HY-P4476
CAS No.: 72682-69-0
Target:  

Ser/Thr Protease

Research Areas:  

Others

Suc-AAPA-pNA is a substrate for chymotrypsin A and elastase. Suc-AAPA-pNA can be used for enzyme activity assay [2] .
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Cat. No.: HY-P3440
CAS No.: 1886057-64-2
Research Areas:  

Cancer

WL12 is a specifically targeting programmed death ligand 1 (PD-L1) binding peptide. WL12 can be radiolabeled by different radionuclides, generating radiotracers, which can assess the tumor PD-L1 expression .
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Cat. No.: HY-106103
CAS No.: 81377-02-8
Purity:  99.30%
Synonyms: MK-678; L-363586
Seglitide (MK-678) is an orally active, selective SSTR2 agonist and somatostatin analog. Seglitide also acts as a competitive Somatostatin receptor antagonist, with pA2 values of 6.50, 6.24 and 6.09 against SS14, SS25 and SS28, respectively. Seglitide produces only weak, transient inhibition of myocardial contractility in isolated right atria of guinea pigs. Seglitide inhibits glucagon secretion and reduces circulating insulin levels. Seglitide causes a sustained, reversible reduction in elevated systolic blood pressure in streptozotocin (HY-13753)-induced diabetic rats, but exerts no effect on spontaneously hypertensive rats. Seglitide induces membrane hyperpolarization and inhibits electrical excitability. Seglitide induces concentration-dependent contraction and significant desensitization in isolated distal colon of rats. Seglitide can be used in research related to hypertension complicated with insulin-dependent diabetes mellitus [2] .
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Cat. No.: HY-P3143
CAS No.: 1629655-80-6
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

BMSpep-57 is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 facilitates T cell function by in creasing IL-2 production in PBMCs .
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Cat. No.: HY-P4460
CAS No.: 60354-61-2
Target:  

Ser/Thr Protease

Research Areas:  

Cancer

AAA-pNA is a chromogenic substrate of Tripeptidyl-peptidase II. AAA-pNA can be used to test Tripeptidyl-peptidase II activity .
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Cat. No.: HY-106103A
CAS No.: 99248-33-6
Purity:  99.30%
Synonyms: MK 678 Acetate; L 36358 Acetate
Seglitide acetate (MK 678; L 36358 acetate) is a potent, orally active somatostatin receptor 2 (SSTR2) agonist, and also a competitive antagonist of SSTR14, SSTR25, and SSTR28. Seglitide acetate has antihypertensive effects and can inhibit plasma glucagon and growth hormone. Seglitide acetate can be used for research on diabetes [2] .
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Cat. No.: HY-P4470
CAS No.: 201738-99-0
Target:  

Ser/Thr Protease

Research Areas:  

Cancer

Phe-Pro-Ala-pNA is a chromogenic substrate of tripeptidyl peptidase. Phe-Pro-Ala-pNA can be used to test tripeptidyl peptidase activity .
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Cat. No.: HY-W014786
CAS No.: 1999-42-4
Research Areas:  

Others

DL-Alanyl-DL-leucine is a dipeptide compound composed of alanine and leucine .
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Cat. No.: HY-125357
CAS No.: 148619-41-4
Target:  

Inhibitory Antibodies

Research Areas:  

Metabolic Disease

Ternatin (compound 2) is a cyclic heptapeptides that can be isolated from mushroom Coliorus versicolor. Ternatin inhibits fat-accumulation with an IC50 of 0.027 μM in 3T3-L1 adipocytes .
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Cat. No.: HY-P5218
CAS No.: 1176133-78-0
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Acetyl dipeptide-3 aminohexanoate is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .
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Cat. No.: HY-P1363S1
β-Amyloid (1-42), human, Ala( 13C3, 15N) TFA is the 13C and 15N-labeled β-Amyloid (1-42), human (HY-P1363A). β-Amyloid (1-42) (Amyloid β-peptide (1-42)), human, a 42-amino acid peptide that has not been treated with HFIP, is a brain-penetrant amyloid protein fragment, which can be used in research on Alzheimer's disease and Down’s syndrome. β-Amyloid (1-42), human remaining as a monomer exhibits antioxidant and neuroprotective effects. β-Amyloid (1-42), human, after being monomericized by HFIP and dissolved in DMSO to form the stock solution, on the one hand, can form soluble oligomers (AβOs) when incubated at 4 °C, which have synaptic toxicity and neurotoxicity; on the other hand, it can be incubated at 37 °C to form insoluble fibrils, with lower neurotoxicity, and participating in the oxidative damage process. Aβ42 oligomers bind to various neuronal surface receptors (such as PrPc, mGluR5, NMDA receptors, etc.), triggering oxidative stress, calcium homeostasis imbalance, and synaptic toxicity via activating downstream signaling pathways, leading to neuronal dysfunction and death [2] .
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Cat. No.: HY-131374
CAS No.: 368874-31-1
Target:  

CXCR

Research Areas:  

Cancer

TN14003 is a CXCR4 inhibitor. TN14003 has antitumor activity .
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Cat. No.: HY-P3143A
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs .
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Cat. No.: HY-P1142S
Research Areas:  

Others

GLP-2(rat) (Ala- 13C3, 15N) is 13C and 15N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).
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Cat. No.: HY-P1142S1
Research Areas:  

Others

GLP-2(rat) (Ala- 13C3, 15N) TFA is 13C and 15N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).
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Cat. No.: HY-158994S
Research Areas:  

Others

MEGDSRGG-(Ala- 13C3, 15N)-GGEA-(Leu- 13C6, 15N)-DPESAASSLSGAS TFA is a 13C- and 15N-labeled peptide containing 13C3, 15N-labeled alanine (Ala) and 13C6, 15N-labeled leucine (Leu).
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Cat. No.: HY-P0058S
Pramlintide-(Ala- 13C3, 15N) is the 13C- and 15N-labeled Pramlintide. Pramlintide is a polypeptide analogue of human amylin. Pramlintide, an antidiabetic agent, is antineoplastic in colorectal cancer .
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Cat. No.: HY-P6696S
Research Areas:  

Others

β-CL, Ala(sup>13C3, 15N) TFA is the 13C- and 15N-labeled β-CL TFA.
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Cat. No.: HY-173103S
FYDPL(Ala- 13C3, 15N)GK TFA is the 13C- and 15N-labeled FYDPL(Ala)GK TFA.
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