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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
Amyloid-β 42
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "Amyloid-β 42" in MCE Product Catalog:
12
12 Cited Publications
Cat. No.: HY-N0373
CAS No.: 58749-23-8
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Research Areas:
Aftin-4 is an Amyloid-β42 (Aβ42) inducer.
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Research Areas:
Aftin-5 is an inducer for Amyloid-β 42 (Aβ42). Aftin-5 upregulates Aβ42 and downregulates Aβ38 levels in a β-secretase- and γ-secretase-dependent manner by altering the ultrastructure of mitochondria. Aftin-5 exhibits slightly cytotoxicity in cell SH-SY5Y, HT22, N2a and N2a-AβPP695, with IC50s of 180, 194, 178 and 150 μM, respectively .
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Cat. No.: HY-W440555
CAS No.: 112269-92-8
Synonyms: para-Sulfonatocalix[n]arene
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Research Areas:
4-Sulfocalix[4]arene (para-Sulfonatocalix[n]arene) is a amyloid-beta 42 binder with a Kd of 5.39 M. 4-Sulfocalix[4]arene can inhibit amyloid β-peptide fibrillation and reduce amyloid cytotoxicity .
Cat. No.: HY-174305
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Research Areas:
Aβ42-IN-7 (Compound CT-01) is a brain-penetrant and selective amyloid-β42 (Aβ42) inhibitor. Aβ42-IN-7 inhibits Aβ42’s assembly into neurotoxic soluble oligomers and extracellular fibrillary aggregates. Aβ42-IN-7 exerts neuroprotective effects by reducing amyloid-mediated neuronal toxicity. Aβ42-IN-7 can be used in research on Alzheimer’s disease (AD) .
Cat. No.: HY-N9379
CAS No.: 70420-58-5
Category:
Alkaloids Monophenols Goniothalamus amuyon (Bl.) Merr. Other Diseases Phenols Plants Annonaceae Disease Research Fields Isoquinoline Alkaloids
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Cat. No.: HY-103537
CAS No.: 1257395-14-4
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Research Areas:
(Rac)-BIIB042 (Compound 10) is an modulator of γ-Secretase. (Rac)-BIIB042 reduces Amyloid-β 42 level with an EC50 value of 0.39 µM. (Rac)-BIIB042 can be used for the study of Alzheimer's disease .
Cat. No.: HY-N6640
CAS No.: 19536-25-5
Synonyms: 20-Hydroxyeedysone 2-acetate
Category:
Target:
Cat. No.: HY-146151
CAS No.: 2204249-82-9
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Research Areas:
γ-Secretase modulator 12 (Compound 1a) is a γ-secretase modulator that can selectively decrease amyloid-β42 (Aβ42) levels (IC50 of 0.39 µM). γ-Secretase modulator 12 can be used for Alzheimer’s disease research. γ-Secretase modulator 12 has a good brain/plasma ratio (Kp, brain = 0.72) in mice .
Cat. No.: HY-N0373R
CAS No.: 58749-23-8
Cat. No.: HY-111267R
CAS No.: 866893-90-5
Target:
Research Areas:
Aftin-4 (Standard) is the analytical standard of Aftin-4 (HY-111267). This product is intended for research and analytical applications. Aftin-4 is an Amyloid-β42 (Aβ42) inducer.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
