35 Results for "

Amyloid-β Precursor Protein

" in MedChemExpress (MCE) Product Catalog:
Products (35)

35 Results for "Amyloid-β Precursor Protein" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-19918A
Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier. Anatabine dicitrate is a potent α4β2 nAChR agonist. Anatabine dicitrate inhibits NF-κB activation lower amyloid-β (Aβ) production by preventing the β-cleavage of amyloid precursor protein (APP). Anatabine dicitrate has anti-inflammatory effects and has the potential for neurodegenerative disorders treatment .
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1
1 Cited Publications
Cat. No.: HY-P704352
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: APP; PreA4; Prev. AD1; CVAP; Alzheimer Disease Amyloid A4 Protein Homolog; Beta-Amyloid Precursor Protein; Amyloid-Beta Precursor Protein; Testicular Tissue Protein Li 2; Amyloid Precursor Protein; Beta-Amyloid Peptide(1-40); Alpha-SAPP; Beta-Amyloid Pept
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-14537
CAS No.: 97657-92-6
Purity:  99.65%
Synonyms: Dimebolin dihydrochloride
Latrepirdine dihydrochloride is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors. Latrepirdine stimulates amyloid precursor protein (APP) catabolism and amyloid-β () secretion.
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Cat. No.: HY-P990301

Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Anti-Human/Mouse/Rat Amyloid-beta Antibody (MOAB-2) is a mouse-derived IgG2b λ type antibody inhibitor, targeting to Amyloid-beta. Anti-Human/Mouse/Rat Amyloid-beta Antibody (MOAB-2) recognizes unaggregated, oligomeric or fibrillar forms of Aβ42 and unaggregated Aβ40. Anti-Human/Mouse/Rat Amyloid-beta Antibody (MOAB-2) is selective for human Aβ42 over Aβ40, but not amyloid precursor protein (APP). Anti-Human/Mouse/Rat Amyloid-beta Antibody (MOAB-2) can immunostain human or rat and mouse tissue. Anti-Human/Mouse/Rat Amyloid-beta Antibody (MOAB-2) can be used for detections of western blot, immunohistochemistry, immunofluorescence, immunoprecipitation and ELISA .
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Cat. No.: HY-14862
CAS No.: 3613-73-8
Synonyms: Dimebolin; Dimebone
Latrepirdine is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors. Latrepirdine stimulates amyloid precursor protein (APP) catabolism and amyloid-β () secretion.
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Cat. No.: HY-P990011
CAS No.: 2747959-38-0
Synonyms: ACU-193

Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Sabirnetug is a humanized IgG2κ antibody targeting the Amyloid-β A4 precursor protein.
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Cat. No.: HY-P4885
CAS No.: 161818-04-8
Synonyms: AβpE3-40
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Glp-Amyloid-β (3-40) Peptide (human) (AβpE3-40) is a minor amounts of pyroglutamate-modified isolated from from 24-month-old Amyloid precursor protein (APP) transgenic Mice .
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Cat. No.: HY-P991130
CAS No.: 2991369-43-6

Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Dalidnetug is a humanized monoclonal antibody targeting human amyloid-beta precursor protein (APP). Dalidnetug specifically binds to APP to reduce the production of amyloid-beta (Aβ), thus exerting the activity of clearing amyloid-beta. Dalidnetug is promising for research of Alzheimer's disease .
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Cat. No.: HY-P10613
CAS No.: 148914-08-3
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

RERMS are bioactive peptides produced from the active regions of amyloid-β and A4 protein precursors that promote fibroblast growth and can be used in the study of neurodegenerative diseases .
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Cat. No.: HY-103538
CAS No.: 62252-26-0
Target:  

Amyloid-β γ-secretase

Research Areas:  

Neurological Disease

JLK-6 is a rhomboid protease GlpG inhibitor. JLK-6 reduces the production of Amyloid β-peptide by altering the cleavage of β-amyloid precursor protein by γ-secretase, with no effect on the cleavage of Notch receptors. JLK-6 can be used in research related to Alzheimer's disease .
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Cat. No.: HY-P2551
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-β(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via post-translational processing of amyloid precursor protein (APP) .
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Cat. No.: HY-14537R
CAS No.: 97657-92-6
Synonyms: Dimebolin dihydrochloride (Standard)
Latrepirdine (dihydrochloride) (Standard) is the analytical standard of Latrepirdine (dihydrochloride). This product is intended for research and analytical applications. Latrepirdine dihydrochloride is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors. Latrepirdine stimulates amyloid precursor protein (APP) catabolism and amyloid-β (Aβ) secretion.
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Cat. No.: HY-126047B
CAS No.: 126454-22-6
(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent α4β2 nAChR agonist . Anatabine inhibits NF-κB activation lower amyloid-β (Aβ) production by preventing the β-cleavage of amyloid precursor protein (APP). Anatabine has anti-inflammatory effects and has the potential for neurodegenerative disorders treatment .
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Cat. No.: HY-130244
CAS No.: 2581114-83-0
Target:  

Beta-secretase

Research Areas:  

Neurological Disease

BACE1-IN-5 (Compound 15) is a β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 9.1 nM, and also inhibits cellular amyloid-β (Aβ) with an IC50 of 0.82 nM. BACE1-IN-5 has a medicinal chemistry that improves hERG inhibition and P-gp efflux .
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Cat. No.: HY-129133
CAS No.: 168037-22-7
cis-Miyabenol C is an isomer of the resveratrol trimer Miyabenol C, which can be isolated from grape herbs. Miyabenol C is an inhibitor of β-amyloid (Aβ) and amyloid β precursor protein (APP) in Alzheimer's disease model mice, and inhibit β-secretase activity without changing the protein level of β-secretase BACE1 .
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Cat. No.: HY-P87606
Synonyms: APPL2, APLP2, Amyloid beta Precursor like Protein 2, APPH, Amyloid beta (A4) Precursor-like Protein 2, Amyloid Protein homolog, Amyloid-like Protein 2, CDEI box-binding Protein, Sperm membrane Protein YWK-II, APLP-2, CDEBP

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, IF-Tissue

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P7522
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: APBA3; Mint-3; Amyloid Beta Precursor Protein Binding Family A Member 3; Amyloid Beta (A4) Precursor Protein-Binding, Family A, Member 3 (X11-Like 2); X11L2; Phosphotyrosine-Binding/-Interacting Domain (PTB)-Bearing Protein; Mint3; Amyloid Beta (A4) Precu
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P75582
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: APLP1; Amyloid-Like Protein 1; Amyloid Beta Precursor Like Protein 1; Amyloid Precursor-Like Protein 1; APLP; CDNA FLJ56046, Highly Similar To Amyloid-Like Protein 1 (APLP)(APLP-1); Amyloid Beta (A4) Precursor-Like Protein 1; APLP-1
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P7502
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: APLP1; Amyloid-Like Protein 1; Amyloid Beta Precursor Like Protein 1; Amyloid Precursor-Like Protein 1; APLP; CDNA FLJ56046, Highly Similar To Amyloid-Like Protein 1 (APLP)(APLP-1); Amyloid Beta (A4) Precursor-Like Protein 1; APLP-1
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P702529
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NAE1; Proto-Oncogene Protein 1; Prev. APPBP1; NEDD8-Activating Enzyme E1 Subunit; APP-BP1; Alternative Protein NAE1; Ula-1; Protooncogene Protein 1; Amyloid Beta Precursor Protein-Binding Protein 1, 59 KDa; A-116A10.1; Amyloid Beta Precursor Protein Bindi
Species:  
Human
Source:  
E. coli
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