Biotin-β-Amyloid (17-40)
Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-β(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via post-translational processing of amyloid precursor protein (APP).
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C120H192N28O33S2
- 分子量:2619.20
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
β-Amyloid (17-40) (5-10 μM) increases the rate of Aβ (1-40) aggregation more than addition of equivalent amounts of β-Amyloid (17-28), because it facilitates aggregation of Aβ40 through two different mechanisms, one promoted by residues 17-21 and the second by residues 30-35[1]. Biotin is widely used throughout the biotechnology industry to conjugate proteins for biochemical assays. Biotin can be used for qualitative and quantitative detection, labelling or immobilisation.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Biotin-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
Biotin-LVFFAEDVGSNKGAIIGLMVGGVV
化学情報
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分子量 2619.20
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分子式 C120H192N28O33S2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Ruitian Liu, et al. Residues 17-20 and 30-35 of beta-amyloid play critical roles in aggregation. J Neurosci Res. 2004 Jan 15;75(2):162-71. [Content Brief]
[2]. J Näslund, et al. The metabolic pathway generating p3, an A beta-peptide fragment, is probably non-amyloidogenic. Biochem Biophys Res Commun. 1994 Oct 28;204(2):780-7 [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
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