APLP2 Antibody (YA7290)
(Synonyms: APPL2, APLP2, Amyloid beta precursor like protein 2, APPH, Amyloid beta (A4) precursor-like protein 2, Amyloid protein homolog, Amyloid-like protein 2, CDEI box-binding protein, Sperm membrane protein YWK-II, APLP-2, CDEBP)APLP2 Antibody (YA7290) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to APLP2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IHC-F, IF-Tissue
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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|---|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:100-200 | 1:100-200 | 1:100-200 |
Product Details
APLP2 Antibody (YA7290) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to APLP2.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 87-140 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 87 kDa
A synthesized peptide derived from human APLP2
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
APLP2 may play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts
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Subcellular Localization
Cell membrane,Nucleus
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Expression
Tissue_Specificity: Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues -
Isoforms & Post-Translational Modification
Q06481 has 6 isomers: Q06481-1: 86956 Da (predicted); Q06481-2: 80721 Da (predicted); Q06481-3: 85487 Da (predicted); Q06481-4: 79238 Da (predicted); Q06481-5: 59151 Da (predicted); Q06481-6: 87215 Da (predicted).
The BPTI/Kunitz inhibitor domain is O-glycosylated -
Subunit
Interacts with CPEB1
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SwissProt ID
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Synonyms
APPL2, APLP2, Amyloid beta precursor like protein 2, APPH, Amyloid beta (A4) precursor-like protein 2, Amyloid protein homolog, Amyloid-like protein 2, CDEI box-binding protein, Sperm membrane protein YWK-II, APLP-2, CDEBP
Documentation
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