168037-22-7
Chemical Structure
cis-Miyabenol C
- CAS No.: 168037-22-7
- Formula:C42H32O9
- Molecular Weight:680.70
IUPAC Name: (2S,2'R,3S,3'R)-3'-(3,5-dihydroxyphenyl)-2,2'-bis(4-hydroxyphenyl)-4-((Z)-4-hydroxystyryl)-2,2',3,3'-tetrahydro-[3,4'-bibenzofuran]-6,6'-diol
InChIKey: RKFYYCKIHVEWHX-LXJGKARHSA-N
SMILES: OC(C=C1)=CC=C1/C=C\C2=C3[C@H](C4=C5[C@@H](C6=CC(O)=CC(O)=C6)[C@H](C7=CC=C(C=C7)O)OC5=CC(O)=C4)[C@@H](C8=CC=C(C=C8)O)OC3=CC(O)=C2
Biological Activity: cis-Miyabenol C is an isomer of the resveratrol trimer Miyabenol C, which can be isolated from grape herbs. Miyabenol C is an inhibitor of β-amyloid (Aβ) and amyloid β precursor protein (APP) in Alzheimer's disease model mice, and inhibit β-secretase activity without changing the protein level of β-secretase BACE1[1][2].
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cis-Miyabenol C | cis-Miyabenol C is an isomer of the resveratrol trimer Miyabenol C, which can be isolated from grape herbs. Miyabenol C is an inhibitor of β-amyloid (Aβ) and amyloid β precursor protein (APP) in Alzheimer's disease model mice, and inhibit β-secretase activity without changing the protein level of β-secretase BACE1. | |||||||||||||||||||||
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