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  3. APLP-1 Protein, Human (171a.a, HEK293, His)

APLP-1 Protein, Human (171a.a, HEK293, His)

Cat. No.: HY-P7502
Handling Instructions

APLP-1 Protein, Human (171a.a, HEK293, His), also known as APLP1, is increased in the frontal cortex of Mn-exposed models.

For research use only. We do not sell to patients.

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Description

APLP-1 Protein, Human (171a.a, HEK293, His), also known as APLP1, is increased in the frontal cortex of Mn-exposed models.

Background

Human APLP-1 gene has been mapped to the long arm of chromosome 19 in the same region containing a late-onset familial AD locus. APLP1 is a member of the amyloid precursor family. Increased APLP1 expression and revealed the presence of amyloid-β diffuse plaques.

Species

Human

Source

HEK293

Tag

C-6*His

Accession

P51693 (G42-P212)

Gene ID

333  [NCBI]

Synonyms
rHuAmyloid-like Protein 1, His; APLP-1; Amyloid-like Protein 1
AA Sequence

GGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPHHHHHH

Molecular Weight

18-20 kDa

Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against PBS, 1 mM EDTA, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O or PBS.

Storage & Stability

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation
References

APLP-1 Protein, Human (171a.a, HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Active Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific active calculator equation

Specific Active (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Active (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
APLP-1 Protein, Human (171a.a, HEK293, His)
Cat. No.:
HY-P7502
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